Pfam Domains mapped on to the structure: 1E3O

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	C	PF00157	Pou domain - N-terminal to homeobox domain	PF00157	PF00157
2	C	PF00046	Homeobox domain	PF00046	PF00046

Gene Ontology Annotations: 1E3O

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0006355	regulation of transcription, DNA-dependent	GO:0006355

Conserved Domain Database Superfamily Annotations: 1E3O

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1E3O	28970	cd00086	homeodomain -	cl00084
2	1E3O	206827	cl00084	homeodomain	superfamily - -
3	1E3O	198730	cl02582	Pou	superfamily - -

Structural Details of PDB entry 1E3O PDBid Chains Hinge Swapped Domain 1E3O A,B A:53-58,B:53-58 A:1-52,B:1-52 Swapped-domain interface residues and interactions: Chains Residues A 1, 2, 3, 4, 5, 6, 7, 8, 11, 39, 40, 45, 49, 54, 55, 56, 57, 58, 59, 154, 157, 158, 159, B 1, 2, 3, 4, 5, 6, 7, 8, 11, 39, 40, 45, 49, 54, 55, 56, 57, 58, 59, 154, 157, 158, 159, Non-swapped-domain interface residues and interactions: Chains Residues A 61, 62, 64, 65, 66, 69, 160, B 61, 62, 64, 65, 66, 69,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1E3O

A:1E3O

B:1E3O

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1E3O.ali
atm file:	1E3O.atm
cof file:	1E3O.cof
hbd file:	1E3O.hbd
html file:	1E3O.html
pdb file:	1E3O.pdb
ps file:	1E3O.ps
psa file:	1E3O.psa
rtf file:	1E3O.rtf
sst file:	1E3O.sst
tem file:	1E3O.tem