Pfam Domains mapped on to the structure: 1DXX
Conserved Domain Database Superfamily Annotations: 1DXX
Structural Details of PDB entry 1DXX
Structural Details of PDB entry 1DXX
PDBid
Chains
Hinge
Swapped Domain
1DXX
A,D,C,B
A:120-136,D:123-135,C:123-135,B:120-136
A:137-246,D:136-246,C:136-246,B:137-246
Swapped-domain interface residues and interactions:
Chains
Residues
A
11 , 12 , 13 , 16 , 17 , 20 , 23 , 24 , 119 , 120 , 123 , 139 , 140 , 160 , 210 , 211 , 212 , 214 , 217 , 220 , 222 , 223 , 224 , 225 , 226 , 227 , 229 , 230 , 233 , 234 , 236 , 237 , 241 , 242 , 243 , 244 , 245 , 246 ,
B
11 , 12 , 13 , 16 , 17 , 20 , 23 , 24 , 119 , 120 , 123 , 139 , 140 , 160 , 210 , 211 , 212 , 214 , 217 , 220 , 222 , 223 , 224 , 225 , 226 , 227 , 229 , 230 , 233 , 234 , 236 , 237 , 241 , 242 , 243 , 244 , 245 , 246 ,
C
11 , 12 , 13 , 16 , 17 , 20 , 23 , 24 , 119 , 120 , 123 , 124 , 136 , 139 , 140 , 160 , 210 , 211 , 212 , 214 , 217 , 220 , 222 , 223 , 224 , 225 , 226 , 227 , 229 , 230 , 233 , 234 , 236 , 237 , 241 , 242 , 243 , 244 , 245 ,
D
11 , 12 , 13 , 16 , 17 , 20 , 23 , 24 , 119 , 120 , 123 , 124 , 136 , 139 , 140 , 160 , 210 , 211 , 212 , 214 , 217 , 220 , 222 , 223 , 224 , 225 , 226 , 227 , 229 , 230 , 233 , 234 , 236 , 237 , 241 , 242 , 243 , 244 , 245 , 246 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
10 , 19 , 21 , 27 , 78 , 81 , 82 , 85 , 88 , 90 , 91 , 92 , 93 , 95 , 96 , 112 , 115 , 122 , 124 , 126 , 127 , 128 , 131 , 132 , 134 , 136 ,
B
10 , 19 , 21 , 27 , 78 , 81 , 82 , 85 , 88 , 90 , 91 , 92 , 93 , 95 , 96 , 112 , 115 , 122 , 124 , 126 , 127 , 128 , 131 , 132 , 134 , 136 ,
C
10 , 19 , 21 , 27 , 78 , 81 , 82 , 85 , 88 , 90 , 91 , 92 , 93 , 95 , 96 , 112 , 115 , 122 , 126 , 127 , 128 , 131 , 132 , 134 ,
D
10 , 19 , 21 , 27 , 78 , 81 , 82 , 85 , 88 , 90 , 91 , 92 , 93 , 95 , 96 , 112 , 115 , 122 , 126 , 127 , 128 , 131 , 132 , 134 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
D No mutation No mutation No mutation No mutation
C No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: