Pfam Domains mapped on to the structure: 1DXE

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03328	HpcH/HpaI aldolase/citrate lyase family	PF03328	PF03328
2	A	PF00224	Pyruvate kinase, barrel domain	PF00224	PF00224

Gene Ontology Annotations: 1DXE

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0006096	glycolysis	GO:0006096

Conserved Domain Database Superfamily Annotations: 1DXE

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1DXE	208991	cl09155	Pyruvate_Kinase	superfamily - -
2	1DXE	208991	cl09155	Pyruvate_Kinase	superfamily - -

Structural Details of PDB entry 1DXE PDBid Chains Hinge Swapped Domain 1DXE A,B A:236-239,B:236-239 A:240-256,B:240-256 Swapped-domain interface residues and interactions: Chains Residues A 35, 36, 39, 40, 41, 240, 242, 243, 244, 246, 247, 248, 250, 251, 253, 254, 255, 256, B 35, 36, 39, 40, 41, 240, 242, 243, 244, 246, 247, 248, 250, 251, 253, 254, 255, Non-swapped-domain interface residues and interactions: Chains Residues A 21, 27, 28, 29, 31, 32, 38, 42, 52, 220, 224, 236, 239, B 19, 21, 27, 28, 29, 31, 32, 38, 42, 52, 220, 224, 236, 239,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1DXE

B:1DXE

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1DXE.ali
atm file:	1DXE.atm
cof file:	1DXE.cof
hbd file:	1DXE.hbd
html file:	1DXE.html
pdb file:	1DXE.pdb
ps file:	1DXE.ps
psa file:	1DXE.psa
rtf file:	1DXE.rtf
sst file:	1DXE.sst
tem file:	1DXE.tem