Pfam Domains mapped on to the structure: 1DQU

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00463	Isocitrate lyase family	PF00463	PF00463
2	A	PF13714	Phosphoenolpyruvate phosphomutase	PF13714	PF13714

Conserved Domain Database Superfamily Annotations: 1DQU

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1DQU	119341	ICL_KPHMT	C	cl00435
2	1DQU	212216	ICL_KPHMT	superfamily	C -
3	1DQU	212216	ICL_KPHMT	superfamily	N -

Structural Details of PDB entry 1DQU PDBid Chains Hinge Swapped Domain 1DQU A,B A:457-459,B:457-459 A:460-520,B:460-520 Swapped-domain interface residues and interactions: Chains Residues A 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 475, 476, 478, 479, 480, 481, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 494, 496, 498, 501, 502, 504, 505, 507, 509, 510, 512, 513, 514, 516, 517, 518, 519, 520, B 461, 462, 463, 464, 465, 466, 467, 468, 469, 470, 471, 472, 473, 475, 476, 478, 479, 480, 481, 483, 484, 485, 486, 487, 488, 489, 490, 491, 492, 494, 496, 498, 501, 502, 504, 505, 507, 509, 510, 512, 513, 514, 516, 517, 518, 519, 520, C 33, 34, 82, 83, 86, 90, 91, 103, 112, 113, 225, 226, 430, 431, 436, 439, 440, 443, 463, 464, 465, 466, 467, 468, 487, 491, 496, 498, D 33, 34, 82, 83, 86, 90, 91, 103, 112, 113, 225, 226, 430, 431, 436, 439, 440, 443, 463, 464, 465, 466, 467, 468, 487, 491, 496, 498, Non-swapped-domain interface residues and interactions: Chains Residues A 3, 4, 5, 7, 8, 11, 14, 33, 34, 38, 41, 42, 43, 44, 45, 46, 48, 49, 51, 54, 74, 76, 79, 80, 81, 82, 83, 86, 90, 91, 99, 103, 104, 108, 109, 110, 111, 112, 113, 114, 115, 117, 119, 120, 121, 128, 129, 132, 133, 135, 136, 138, 139, 142, 143, 145, 146, 147, 150, 153, 154, 158, 162, 174, 175, 176, 177, 178, 180, 181, 184, 185, 188, 189, 201, 202, 204, 218, 219, 222, 225, 226, 229, 230, 233, 254, 255, 256, 258, 274, 276, 277, 280, 283, 292, 341, 360, 363, 365, 366, 367, 369, 424, 426, 427, 429, 430, 431, 436, 439, 440, 443, 456, 458, 459, B 3, 4, 5, 7, 8, 11, 14, 33, 34, 38, 41, 42, 43, 44, 45, 46, 48, 49, 51, 54, 74, 76, 79, 80, 81, 82, 83, 86, 90, 91, 99, 103, 104, 108, 109, 110, 111, 112, 113, 114, 115, 117, 119, 120, 121, 128, 129, 132, 133, 135, 136, 138, 139, 142, 143, 145, 146, 147, 150, 153, 154, 158, 162, 174, 175, 176, 177, 178, 180, 181, 184, 185, 188, 189, 201, 202, 204, 218, 219, 222, 225, 226, 229, 230, 233, 254, 255, 256, 258, 274, 276, 277, 280, 283, 292, 341, 360, 363, 365, 366, 367, 369, 424, 426, 427, 429, 430, 431, 436, 439, 440, 443, 456, 458, 459, C 3, 4, 5, 7, 8, 11, 14, 38, 41, 42, 43, 44, 45, 46, 48, 49, 51, 54, 74, 76, 79, 80, 81, 99, 104, 108, 109, 110, 111, 114, 115, 117, 119, 120, 121, 128, 129, 132, 133, 135, 136, 138, 139, 142, 143, 145, 146, 147, 150, 153, 154, 158, 162, 174, 175, 176, 177, 178, 180, 181, 184, 185, 188, 189, 201, 202, 204, 218, 219, 222, 229, 230, 233, 254, 255, 256, 258, 274, 276, 277, 280, 283, 292, 341, 360, 363, 365, 366, 367, 369, 424, 426, 427, 429, 456, 458, 459, 461, 462, 469, 470, 471, 472, 473, 475, 476, 478, 479, 480, 481, 483, 484, 485, 486, 488, 489, 490, 492, 494, 501, 502, 504, 505, 507, 509, 510, 512, 513, 514, 516, 517, 518, 519, 520, D 3, 4, 5, 7, 8, 11, 14, 38, 41, 42, 43, 44, 45, 46, 48, 49, 51, 54, 74, 76, 79, 80, 81, 99, 104, 108, 109, 110, 111, 114, 115, 117, 119, 120, 121, 128, 129, 132, 133, 135, 136, 138, 139, 142, 143, 145, 146, 147, 150, 153, 154, 158, 162, 174, 175, 176, 177, 178, 180, 181, 184, 185, 188, 189, 201, 202, 204, 218, 219, 222, 229, 230, 233, 254, 255, 256, 258, 274, 276, 277, 280, 283, 292, 341, 360, 363, 365, 366, 367, 369, 424, 426, 427, 429, 456, 458, 459, 461, 462, 469, 470, 471, 472, 473, 475, 476, 478, 479, 480, 481, 483, 484, 485, 486, 488, 489, 490, 492, 494, 501, 502, 504, 505, 507, 509, 510, 512, 513, 514, 516, 517, 518, 519,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1DQU

D:1DQU

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1DQU.ali
atm file:	1DQU.atm
pdb file:	1DQU.pdb
psa file:	1DQU.psa
sst file:	1DQU.sst