3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1DCI

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00378 Enoyl-CoA hydratase/isomerase family PF00378 PF00378

Conserved Domain Database Superfamily Annotations: 1DCI

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1DCI 119339 cd06558 crotonase-like - cl15762

2 1DCI 210162 cl15762 crotonase-like superfamily - -

3 1DCI 210162 cl15762 crotonase-like superfamily - -

Structural Details of PDB entry 1DCI

Structural Details of PDB entry 1DCI

PDBid Chains Hinge Swapped Domain

1DCI A,B A:284-287,B:284-287 A:288-327,B:288-327

Swapped-domain interface residues and interactions:

Chains Residues
A 119, 127, 138, 141, 142, 145, 198, 199, 200, 201, 204, 209, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 309, 310, 313, 314, 319, 325, 326, 327,

B 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 309, 310, 313, 314, 319, 325, 326, 327,

C 138, 141, 142, 145, 146, 198, 199, 200, 201, 204, 206, 209,

D 295, 296, 299,

E 133, 134, 135, 136, 138, 295, 296, 299,

F 133, 134, 135, 136, 138,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 97, 120, 122, 123, 126, 132, 133, 134, 135, 136, 137, 139, 149, 153, 157, 159, 161, 182, 183, 184, 185, 197, 202, 208, 210, 212, 213, 214, 215, 216, 217, 218, 219, 221, 222, 223, 225, 226, 227, 240, 243, 259, 262, 263, 266, 267, 269, 270, 271, 273, 274, 276, 277, 278, 280, 281, 282, 283, 284, 285, 286, 287,

B 97, 119, 120, 122, 123, 126, 127, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 145, 149, 153, 157, 159, 161, 182, 183, 184, 197, 198, 199, 200, 201, 202, 204, 206, 208, 209, 210, 212, 213, 214, 215, 216, 217, 218, 219, 220, 222, 223, 225, 226, 227, 240, 243, 259, 262, 263, 266, 267, 269, 270, 271, 273, 274, 275, 277, 278, 280, 281, 282, 283, 284, 285, 286, 287,

C 119, 120, 122, 126, 127, 132, 133, 134, 135, 136, 137, 139, 143, 149, 153, 157, 159, 161, 182, 183, 184, 185, 197, 202, 208, 210, 212, 213, 214, 215, 216, 217, 218, 219, 220, 222, 223, 225, 226, 227, 240, 243, 259, 262, 263, 266, 267, 269, 270, 271, 273, 274, 277, 278, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 309, 310, 313, 314, 319, 325, 326, 327,

D 97, 119, 120, 122, 123, 126, 127, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 145, 149, 153, 157, 159, 161, 182, 183, 184, 185, 197, 198, 199, 200, 201, 202, 204, 208, 209, 210, 212, 213, 214, 215, 216, 217, 218, 219, 221, 222, 223, 225, 226, 227, 240, 243, 259, 262, 263, 266, 267, 269, 270, 271, 273, 274, 276, 277, 278, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 297, 298, 300, 301, 302, 303, 304, 305, 306, 307, 309, 310, 313, 314, 319, 325, 326, 327,

E 119, 120, 122, 126, 127, 132, 137, 139, 141, 142, 143, 145, 146, 149, 153, 157, 159, 161, 182, 183, 184, 185, 197, 198, 199, 200, 201, 202, 204, 206, 208, 209, 210, 212, 213, 214, 215, 216, 217, 218, 219, 220, 222, 223, 225, 226, 227, 240, 243, 259, 262, 263, 266, 267, 269, 270, 271, 273, 274, 277, 278, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 297, 298, 300, 301, 302, 303, 304, 305, 306, 307, 309, 310, 313, 314, 319, 325, 326, 327,

F 97, 119, 120, 122, 123, 126, 127, 132, 137, 139, 141, 142, 143, 145, 149, 153, 157, 159, 161, 182, 183, 184, 197, 198, 199, 200, 201, 202, 204, 206, 208, 209, 210, 212, 213, 214, 215, 216, 217, 218, 219, 220, 222, 223, 225, 226, 227, 240, 243, 259, 262, 263, 266, 267, 269, 270, 271, 273, 274, 275, 277, 278, 280, 281, 282, 283, 284, 285, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 306, 307, 309, 310, 313, 314, 319, 325, 326,

Swapped domains are represented using trasperent spheres.
Non-swapped part is reprented using light color and cartoon reprentation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:1DCI A:1DCI F:1DCI

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1DCI.ali
atm file: 1DCI.atm
cof file: 1DCI.cof
hbd file: 1DCI.hbd
html file: 1DCI.html
pdb file: 1DCI.pdb
ps file: 1DCI.ps
psa file: 1DCI.psa
rtf file: 1DCI.rtf
sst file: 1DCI.sst
tem file: 1DCI.tem