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Pfam Domains mapped on to the structure: 1D6S

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 A PF00291 Pyridoxal-phosphate dependent enzyme PF00291 PF00291

Conserved Domain Database Superfamily Annotations: 1D6S

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 1D6S 107204 cd01561 CBS_like - cl00342
2 1D6S 212605 cl00342 Trp-synth-beta_II superfamily - -
3 1D6S 212605 cl00342 Trp-synth-beta_II superfamily - -
Structural Details of PDB entry 1D6S

Structural Details of PDB entry 1D6S

PDBid Chains Hinge Swapped Domain
1D6S A,B A:266-269,B:266-269 A:270-322,B:270-322

Swapped-domain interface residues and interactions:

Chains Residues
A 97, 100, 101, 301, 303, 304, 306, 311, 314, 315, 316, 318, 319, 320, 322,
B 93, 97, 100, 101, 301, 303, 304, 306, 311, 314, 315, 316, 318, 319, 320, 321,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 1, 2, 3, 4, 5, 6, 7, 10, 12, 15, 16, 17, 18, 20, 21, 28, 31, 33, 34, 36, 37, 38, 78, 81, 82, 93, 98, 102, 104, 105, 106, 107, 110, 112, 163, 164, 165, 262, 263, 265, 266, 267, 268,
B 1, 2, 3, 4, 5, 6, 7, 10, 15, 16, 17, 18, 20, 28, 31, 33, 34, 36, 37, 38, 78, 81, 82, 84, 98, 102, 104, 105, 106, 107, 110, 112, 163, 164, 165, 262, 263, 264, 265, 266, 267, 268,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
AGLY(266)VAL, ILE(267)PHE, No mutationGLY(266)VAL, ILE(267)PHE, No mutation
BGLY(266)VAL, ILE(267)PHE, No mutationGLY(266)VAL, ILE(267)PHE, No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

A:1D6S B:1D6S

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:1D6S.ali
atm file:1D6S.atm
cof file:1D6S.cof
hbd file:1D6S.hbd
html file:1D6S.html
pdb file:1D6S.pdb
ps file:1D6S.ps
psa file:1D6S.psa
rtf file:1D6S.rtf
sst file:1D6S.sst
tem file:1D6S.tem