Pfam Domains mapped on to the structure: 1D6S
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00291
Pyridoxal-phosphate dependent enzyme
PF00291
PF00291
Conserved Domain Database Superfamily Annotations: 1D6S
Structural Details of PDB entry 1D6S
Structural Details of PDB entry 1D6S
PDBid
Chains
Hinge
Swapped Domain
1D6S
A,B
A:266-269,B:266-269
A:270-322,B:270-322
Swapped-domain interface residues and interactions:
Chains
Residues
A
97 , 100 , 101 , 301 , 303 , 304 , 306 , 311 , 314 , 315 , 316 , 318 , 319 , 320 , 322 ,
B
93 , 97 , 100 , 101 , 301 , 303 , 304 , 306 , 311 , 314 , 315 , 316 , 318 , 319 , 320 , 321 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
1 , 2 , 3 , 4 , 5 , 6 , 7 , 10 , 12 , 15 , 16 , 17 , 18 , 20 , 21 , 28 , 31 , 33 , 34 , 36 , 37 , 38 , 78 , 81 , 82 , 93 , 98 , 102 , 104 , 105 , 106 , 107 , 110 , 112 , 163 , 164 , 165 , 262 , 263 , 265 , 266 , 267 , 268 ,
B
1 , 2 , 3 , 4 , 5 , 6 , 7 , 10 , 15 , 16 , 17 , 18 , 20 , 28 , 31 , 33 , 34 , 36 , 37 , 38 , 78 , 81 , 82 , 84 , 98 , 102 , 104 , 105 , 106 , 107 , 110 , 112 , 163 , 164 , 165 , 262 , 263 , 264 , 265 , 266 , 267 , 268 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A GLY(266)VAL, ILE(267)PHE, No mutation GLY(266)VAL, ILE(267)PHE, No mutation
B GLY(266)VAL, ILE(267)PHE, No mutation GLY(266)VAL, ILE(267)PHE, No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: