3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1CAX

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00190 Cupin PF00190 PF00190

2 A PF07883 Cupin domain PF07883 PF07883

3 B PF00190 Cupin PF00190 PF00190

Gene Ontology Annotations: 1CAX

No. GO ID GO Description Linkout - AmiGO

1 GO:0045735 nutrient reservoir activity GO:0045735

Conserved Domain Database Superfamily Annotations: 1CAX

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1CAX 212615 cl09118 Cupin_2 superfamily - -

Structural Details of PDB entry 1CAX

Structural Details of PDB entry 1CAX

PDBid Chains Hinge Swapped Domain

1CAX E,B E:166-186,B:166-186;E:211-218,B:211-218 E:187-210,B:187-210

Swapped-domain interface residues and interactions:

Chains Residues
B 316, 318, 334, 335, 380, 399, 400, 401, 406, 412, 413, 419, 421, 423,

E 187, 189, 190, 191, 192, 193, 194, 196, 197, 198, 199, 200, 201, 202, 205, 206, 208, 209,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 48, 49, 50, 51, 52, 53, 54, 56, 57, 58, 59, 69, 72, 73, 75, 78, 79, 80, 81, 82, 83, 86, 87, 88, 90, 98, 100, 101, 103, 105, 107, 109, 111, 113, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 145, 147, 158, 160, 162, 164, 166, 167, 168, 169, 171, 172, 173, 174, 175, 177, 178, 182, 183, 184, 186, 187, 189, 190, 191, 192, 193, 194, 196, 197, 198, 199, 200, 201, 203, 206, 208, 209, 210, 212, 214, 218, 220, 222, 223, 224,

B 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 254, 255, 256, 257, 271, 272, 273, 274, 275, 276, 277, 278, 279, 281, 283, 293, 296, 298, 300, 301, 303, 305, 307, 309, 314, 317, 320, 321, 322, 323, 324, 326, 328, 329, 331, 332, 333, 336, 338, 340, 342, 343, 344, 345, 346, 347, 349, 350, 351, 352, 353, 355, 357, 365, 367, 369, 370, 373, 375, 377, 379, 383, 384, 386, 387, 388, 389, 390, 391, 393, 394, 397, 398, 405, 408, 409, 410, 414, 424,

C 49, 50, 51, 52, 53, 54, 56, 57, 58, 59, 60, 69, 70, 72, 73, 75, 78, 79, 80, 81, 82, 83, 86, 88, 90, 98, 100, 101, 103, 105, 107, 109, 111, 113, 122, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 144, 145, 147, 158, 160, 162, 164, 166, 167, 168, 169, 171, 172, 173, 174, 175, 177, 178, 182, 183, 184, 186, 187, 189, 190, 191, 192, 193, 194, 196, 197, 198, 199, 200, 201, 205, 206, 208, 209, 210, 212, 214, 220, 222, 223, 224,

D 241, 242, 244, 245, 247, 248, 250, 251, 252, 271, 272, 275, 276, 279, 281, 283, 293, 296, 298, 300, 301, 303, 305, 307, 309, 316, 317, 318, 320, 321, 322, 323, 324, 326, 327, 328, 329, 331, 332, 333, 335, 336, 338, 339, 340, 343, 344, 345, 346, 347, 349, 350, 351, 352, 353, 355, 357, 363, 365, 367, 369, 370, 375, 377, 379, 380, 381, 383, 384, 386, 387, 389, 390, 391, 393, 394, 397, 398, 399, 400, 401, 405, 406, 409, 410, 412, 413, 419, 420, 422, 423, 424,

E 49, 50, 51, 52, 53, 54, 56, 57, 59, 60, 69, 70, 72, 73, 79, 80, 81, 82, 83, 86, 87, 88, 90, 98, 100, 101, 103, 105, 107, 109, 111, 113, 116, 118, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 144, 145, 147, 151, 152, 158, 160, 162, 164, 166, 167, 168, 169, 171, 172, 173, 174, 175, 177, 178, 182, 183, 184, 186, 212, 214, 220, 222, 223, 224,

F 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 275, 276, 278, 279, 281, 283, 293, 295, 296, 298, 300, 301, 303, 305, 307, 309, 316, 317, 318, 319, 320, 321, 322, 323, 324, 326, 327, 328, 329, 331, 332, 333, 334, 335, 336, 338, 339, 343, 344, 345, 346, 347, 349, 350, 351, 352, 353, 355, 357, 363, 365, 367, 369, 370, 373, 375, 377, 379, 380, 384, 386, 387, 389, 390, 391, 393, 394, 397, 398, 399, 400, 401, 405, 406, 409, 410, 412, 413, 419, 421, 423, 424,

G 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 275, 276, 278, 279, 281, 283, 293, 295, 296, 298, 300, 301, 303, 305, 307, 309, 316, 317, 318, 319, 320, 321, 322, 323, 324, 326, 327, 328, 329, 331, 332, 333, 334, 335, 336, 338, 339, 343, 344, 345, 346, 347, 349, 350, 351, 352, 353, 355, 357, 363, 365, 367, 369, 370, 373, 375, 377, 379, 380, 384, 386, 387, 389, 390, 391, 393, 394, 397, 398, 399, 400, 401, 405, 406, 409, 410, 412, 413, 419, 421, 423, 424,

H 49, 50, 51, 52, 53, 54, 56, 57, 58, 59, 60, 69, 70, 72, 73, 75, 78, 79, 80, 81, 82, 83, 86, 88, 90, 98, 100, 101, 103, 105, 107, 109, 111, 113, 122, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 144, 145, 147, 158, 160, 162, 164, 166, 167, 168, 169, 171, 172, 173, 174, 175, 177, 178, 182, 183, 184, 186, 187, 189, 190, 191, 192, 193, 194, 196, 197, 198, 199, 200, 201, 205, 206, 208, 209, 210, 212, 214, 220, 222, 223, 224,

I 49, 50, 51, 52, 53, 54, 56, 57, 59, 60, 69, 70, 72, 73, 79, 80, 81, 82, 83, 86, 87, 88, 90, 98, 100, 101, 103, 105, 107, 109, 111, 113, 116, 118, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 144, 145, 147, 151, 152, 158, 160, 162, 164, 166, 167, 168, 169, 171, 172, 173, 174, 175, 177, 178, 182, 183, 184, 186, 187, 189, 190, 191, 192, 193, 194, 196, 197, 198, 199, 200, 201, 202, 205, 206, 208, 209, 212, 214, 220, 222, 223, 224,

J 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 254, 255, 256, 257, 271, 272, 273, 274, 275, 276, 277, 278, 279, 281, 283, 293, 296, 298, 300, 301, 303, 305, 307, 309, 314, 316, 317, 318, 320, 321, 322, 323, 324, 326, 328, 329, 331, 332, 333, 334, 335, 336, 338, 340, 342, 343, 344, 345, 346, 347, 349, 350, 351, 352, 353, 355, 357, 365, 367, 369, 370, 373, 375, 377, 379, 380, 383, 384, 386, 387, 388, 389, 390, 391, 393, 394, 397, 398, 399, 400, 401, 405, 406, 408, 409, 410, 412, 413, 414, 419, 421, 423, 424,

K 241, 242, 244, 245, 247, 248, 250, 251, 252, 271, 272, 275, 276, 279, 281, 283, 293, 296, 298, 300, 301, 303, 305, 307, 309, 316, 317, 318, 320, 321, 322, 323, 324, 326, 327, 328, 329, 331, 332, 333, 335, 336, 338, 339, 340, 343, 344, 345, 346, 347, 349, 350, 351, 352, 353, 355, 357, 363, 365, 367, 369, 370, 375, 377, 379, 380, 381, 383, 384, 386, 387, 389, 390, 391, 393, 394, 397, 398, 399, 400, 401, 405, 406, 409, 410, 412, 413, 419, 420, 422, 423, 424,

L 48, 49, 50, 51, 52, 53, 54, 56, 57, 58, 59, 69, 72, 73, 75, 78, 79, 80, 81, 82, 83, 86, 87, 88, 90, 98, 100, 101, 103, 105, 107, 109, 111, 113, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 133, 134, 135, 136, 137, 138, 139, 141, 142, 143, 145, 147, 158, 160, 162, 164, 166, 167, 168, 169, 171, 172, 173, 174, 175, 177, 178, 182, 183, 184, 186, 187, 189, 190, 191, 192, 193, 194, 196, 197, 198, 199, 200, 201, 203, 206, 208, 209, 210, 212, 214, 218, 220, 222, 223,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

E No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

E:1CAX L:1CAX

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1CAX.ali
atm file: 1CAX.atm
pdb file: 1CAX.pdb
psa file: 1CAX.psa
sst file: 1CAX.sst