3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 1B9M

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00126 Bacterial regulatory helix-turn-helix protein, lysR family PF00126 PF00126

2 A PF03459 TOBE domain PF03459 PF03459

3 A PF03459 TOBE domain PF03459 PF03459

Gene Ontology Annotations: 1B9M

No. GO ID GO Description Linkout - AmiGO

1 GO:0043190 ATP-binding cassette (ABC) transporter complex GO:0043190

Conserved Domain Database Superfamily Annotations: 1B9M

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 1B9M 212173 cl00088 HTH superfamily - -

2 1B9M 207413 cl01440 TOBE_2 superfamily - -

3 1B9M 207413 cl01440 TOBE_2 superfamily - -

4 1B9M 207413 cl01440 TOBE_2 superfamily - -

Structural Details of PDB entry 1B9M

Structural Details of PDB entry 1B9M

PDBid Chains Hinge Swapped Domain

1B9M A,B A:105-112,B:105-112 A:1-104,B:1-104

Swapped-domain interface residues and interactions:

Chains Residues
A 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 61, 80, 81, 84, 85, 87, 88, 91, 92, 95, 96, 99, 100, 103, 104, 111, 112, 114,

B 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 61, 80, 81, 84, 85, 87, 88, 90, 91, 92, 94, 95, 98, 99, 100, 102, 103, 104, 111, 114,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 106, 107, 108, 109, 110, 117, 118, 121, 122, 123, 124, 125, 126, 127, 128, 161, 162, 166, 169, 170, 181, 183, 254, 255, 256, 257, 258, 259, 260, 261, 262,

B 105, 106, 108, 112, 115, 118, 119, 122, 123, 124, 125, 126, 127, 161, 162, 166, 169, 170, 181, 183, 186, 254, 256, 257, 258, 259, 260, 261,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1B9M B:1B9M

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 1B9M.ali
atm file: 1B9M.atm
cof file: 1B9M.cof
hbd file: 1B9M.hbd
html file: 1B9M.html
pdb file: 1B9M.pdb
ps file: 1B9M.ps
psa file: 1B9M.psa
rtf file: 1B9M.rtf
sst file: 1B9M.sst
tem file: 1B9M.tem