Pfam Domains mapped on to the structure: 1B4K
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00490
Delta-aminolevulinic acid dehydratase
PF00490
PF00490
Conserved Domain Database Superfamily Annotations: 1B4K
Structural Details of PDB entry 1B4K
Structural Details of PDB entry 1B4K
PDBid
Chains
Hinge
Swapped Domain
1B4K
A,B
A:30-37,B:30-37
A:10-29,B:6-29
Swapped-domain interface residues and interactions:
Chains
Residues
A
10 , 15 , 16 , 19 , 20 , 25 , 28 , 29 , 179 , 180 , 230 , 231 , 232 , 237 , 238 ,
B
8 , 10 , 14 , 15 , 16 , 19 , 20 , 25 , 28 , 29 , 179 , 180 , 231 , 232 , 237 , 238 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
30 , 31 , 55 , 56 , 58 , 147 , 150 , 151 , 209 , 210 , 212 , 213 , 235 , 236 , 239 , 240 , 241 , 244 , 245 , 248 , 252 , 263 , 264 , 265 , 266 , 267 , 270 , 271 , 287 , 290 , 291 , 292 , 294 , 295 , 300 , 301 , 302 , 304 , 305 , 308 , 311 , 312 , 315 , 316 , 335 ,
B
30 , 31 , 55 , 56 , 58 , 147 , 177 , 178 , 209 , 210 , 212 , 213 , 235 , 236 , 239 , 240 , 241 , 244 , 245 , 248 , 252 , 263 , 264 , 265 , 266 , 267 , 270 , 271 , 287 , 290 , 291 , 292 , 294 , 295 , 300 , 301 , 302 , 304 , 305 , 308 , 311 , 312 , 315 , 316 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: