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Pfam Domains mapped on to the structure: 1AQK

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 L PF13927 Immunoglobulin domain PF13927 PF13927

Conserved Domain Database Superfamily Annotations: 1AQK

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 1AQK 143182 cd04981 IgV_H - cl11960
2 1AQK 212623 cl11960 Ig superfamily - -
3 1AQK 143186 cd04985 IgC_CH1 - cl11960
4 1AQK 212623 cl11960 Ig superfamily - -
5 1AQK 212623 cl11960 Ig superfamily - -
Structural Details of PDB entry 1AQK

Structural Details of PDB entry 1AQK

PDBid Chains Hinge Swapped Domain
1AQK H,L H:42-45,L:43-46 H:2-41,L:2-42

Swapped-domain interface residues and interactions:

Chains Residues
H 39, 109,
L 33, 34, 36, 38, 40, 42,

Non-swapped-domain interface residues and interactions:

Chains Residues
H 44, 45, 47, 57, 59, 95, 100, 101, 106, 107, 108, 110, 111, 113, 114, 115, 132, 133, 134, 135, 139, 140, 147, 151, 153, 174, 176, 177, 179, 181, 182, 187, 189, 191, 219,
L 45, 46, 48, 51, 89, 93, 96, 97, 98, 99, 101, 103, 120, 121, 122, 123, 125, 127, 128, 131, 133, 135, 137, 139, 141, 164, 166, 169, 171, 177, 178, 179, 181, 183, 208, 209, 210, 213, 215, 216,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
HNo mutationPRO(109)TYR, LYS(57)ASN, LEU(100)-, PHE(101)GLU, LEU(106)ARG, ALA(108)TYR, ASN(30)SER, ALA(33)GLY, ILE(34)MET,
LNo mutationPHE(33)HIS, THR(34)HIS, HIS(40)GLN, PHE(51)TYR, TYR(93)PHE, ALA(99)TRP, ALA(213)THR, ARG(17)LYS, VAL(18)ILE, THR(23)SER, SER(25)THR, ASN(26)SER, PHE(33)HIS, THR(34)HIS, HIS(40)GLN, LEU(41)VAL,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

H:1AQK

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:1AQK.ali
atm file:1AQK.atm
cof file:1AQK.cof
hbd file:1AQK.hbd
pdb file:1AQK.pdb
psa file:1AQK.psa
sst file:1AQK.sst