Pfam Domains mapped on to the structure: 1AGQ
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00019
Transforming growth factor beta like domain
PF00019
PF00019
Conserved Domain Database Superfamily Annotations: 1AGQ
Structural Details of PDB entry 1AGQ
Structural Details of PDB entry 1AGQ
PDBid Chains Hinge Swapped Domain
1AGQ
A,D,C,B
A:70-73,D:70-73,C:70-73,B:70-73
A:74-91,D:74-91,C:74-91,B:74-91
Swapped-domain interface residues and interactions:
Chains Residues
A
54 , 55 , 78 , 79 , 80 , 81 , 83 , 84 , 86 , 87 , 90 , 91 , 126 , 127 ,
B
54 , 55 , 78 , 79 , 80 , 81 , 83 , 86 , 87 , 125 , 126 , 127 ,
C
54 , 55 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 86 , 87 , 125 , 126 , 127 ,
D
54 , 55 , 78 , 79 , 80 , 81 , 83 , 84 , 86 , 87 , 124 , 125 , 126 , 127 ,
Non-swapped-domain interface residues and interactions:
Chains Residues
A
47 , 49 , 53 , 56 , 66 , 68 , 69 , 70 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 108 , 124 , 125 , 135 ,
B
40 , 41 , 43 , 44 , 45 , 46 , 47 , 49 , 53 , 56 , 66 , 68 , 69 , 70 , 92 , 93 , 98 , 99 , 100 , 102 , 103 , 104 , 105 , 108 , 124 , 135 ,
C
47 , 49 , 53 , 56 , 66 , 68 , 69 , 70 , 92 , 93 , 98 , 99 , 100 , 102 , 103 , 104 , 105 , 108 , 124 , 129 , 135 ,
D
42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 53 , 56 , 65 , 66 , 67 , 68 , 69 , 70 , 92 , 93 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 108 , 132 ,
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation No mutation No mutation No mutation D No mutation No mutation No mutation No mutation C No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
