Pfam Domains mapped on to the structure: 1AD3

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00171	Aldehyde dehydrogenase family	PF00171	PF00171
2	A	PF05893	Acyl-CoA reductase (LuxC)	PF05893	PF05893

Conserved Domain Database Superfamily Annotations: 1AD3

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1AD3	143450	cd07132	ALDH_F3AB -	cl11961
2	1AD3	212336	cl11961	ALDH-SF	superfamily - -
3	1AD3	212336	cl11961	ALDH-SF	superfamily - -

Structural Details of PDB entry 1AD3 PDBid Chains Hinge Swapped Domain 1AD3 A,B A:80-84,B:80-84;A:101-106,B:101-106 A:85-100,B:85-100 Swapped-domain interface residues and interactions: Chains Residues A 86, 87, 89, 91, 97, 98, 99, 100, 398, B 86, 87, 89, 91, 97, 98, 99, 100, 398, Non-swapped-domain interface residues and interactions: Chains Residues A 20, 56, 68, 102, 104, 179, 181, 193, 196, 197, 200, 201, 203, 204, 205, 210, 223, 226, 229, 230, 233, 269, 270, 280, 358, 359, 368, 370, 373, 374, 377, 378, 379, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 392, 393, 395, 396, 397, 399, 400, 403, 404, 405, 406, 409, 423, 425, 426, 427, 428, 429, 430, 431, 433, 436, 438, 439, 440, 441, 442, 443, 444, 445, 446, 447, B 20, 56, 68, 102, 103, 104, 179, 181, 193, 196, 197, 200, 201, 203, 204, 205, 210, 223, 226, 229, 230, 233, 269, 270, 280, 358, 359, 368, 370, 373, 374, 377, 378, 380, 381, 382, 383, 384, 385, 386, 387, 388, 389, 392, 393, 395, 396, 397, 399, 400, 403, 404, 405, 406, 409, 423, 425, 426, 427, 428, 429, 430, 431, 433, 436, 438, 439, 440, 441, 442, 443, 444, 445, 446,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1AD3

B:1AD3

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1AD3.ali
atm file:	1AD3.atm
cof file:	1AD3.cof
hbd file:	1AD3.hbd
html file:	1AD3.html
pdb file:	1AD3.pdb
ps file:	1AD3.ps
psa file:	1AD3.psa
rtf file:	1AD3.rtf
sst file:	1AD3.sst
tem file:	1AD3.tem