Pfam Domains mapped on to the structure: 1A2W

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00074	Pancreatic ribonuclease	PF00074	PF00074

Conserved Domain Database Superfamily Annotations: 1A2W

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	1A2W	119387	cd06265	RNase_A_canonical -	cl00128
2	1A2W	206850	cl00128	RNase_A	superfamily - -

Structural Details of PDB entry 1A2W PDBid Chains Hinge Swapped Domain 1A2W A,B A:15-22,B:15-22 A:1-14,B:1-14 Swapped-domain interface residues and interactions: Chains Residues A 4, 5, 7, 8, 9, 10, 11, 12, 13, 14, 33, 45, 46, 47, 48, 116, 117, 118, 119, B 4, 5, 8, 9, 10, 11, 12, 13, 14, 33, 45, 46, 47, 48, 116, 117, 118, Non-swapped-domain interface residues and interactions: Chains Residues A 15, 17, 18, 19, 20, 21, 23, 25, 29, 34, 35, 41, 44, 49, 50, 51, 54, 80, 85, 98, 99, 100, 101, 102, 103, 104, 120, 124, B 15, 19, 20, 22, 23, 24, 25, 27, 29, 34, 35, 41, 44, 49, 50, 51, 54, 80, 87, 89, 98, 99, 100, 101, 102, 120,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:1A2W

B:1A2W

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	1A2W.ali
atm file:	1A2W.atm
cof file:	1A2W.cof
hbd file:	1A2W.hbd
html file:	1A2W.html
pdb file:	1A2W.pdb
ps file:	1A2W.ps
psa file:	1A2W.psa
rtf file:	1A2W.rtf
sst file:	1A2W.sst
tem file:	1A2W.tem