HEADER SERINE KINASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: TITIN; COMPND 3 CHAIN: A, B; COMPND 4 FRAGMENT: KINASE; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGAN: HEART; SOURCE 5 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA INSECT CELLS; SOURCE 6 EXPRESSION_SYSTEM_CELL_LINE: SF9; SOURCE 7 EXPRESSION_SYSTEM_VECTOR: BACULOVIRUS RESOLUTION SOURCE : EMBL/DESY, HAMBURG AUTHOR M.O.MAYANS,M.GAUTEL,M.WILMANNS RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION JRNL AUTH O.MAYANS,P.F.VAN DER VEN,M.WILM,A.MUES,P.YOUNG, JRNL AUTH 2 D.O.FURST,M.WILMANNS,M.GAUTEL JRNL TITL STRUCTURAL BASIS FOR ACTIVATION OF THE TITIN KINASE JRNL TITL 2 DOMAIN DURING MYOFIBRILLOGENESIS JRNL REF NATURE V. 395 863 1998 JRNL REFN ASTM NATUAS UK ISSN 0028-0836 0006 RESOLUTION 2.0 ANGSTROMS.

Sequence in PIR format:

>P1;1tkiA structureX:1tkiA: 18 :A: 338 :A:titin:homo sapiens: 9.99: 9.99 KELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIARHRNILHLHESFESMEE LVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQ ARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEE AFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKDLNMVVSAARIS CGGAIRSQKGVSVAKVKVASI*

View SSTRUC file for 1tkiA

Rasmol View of 1tkiA