HEADER HYDROLASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: M-PHASE INDUCER PHOSPHATASE 2 (CDC25B); COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: CATALYTIC DOMAIN; COMPND 5 EC: 3.1.3.48; COMPND 6 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 CELLULAR_LOCATION: CYTOPLASM; SOURCE 5 GENE: CDC25B; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: JM109; SOURCE 9 EXPRESSION_SYSTEM_VECTOR: XL1-BLUE RESOLUTION SOURCE : ROTATING ANODE AUTHOR K.D.WATENPAUGH,R.A.REYNOLDS RESOLUTION : G.M.SHELDRICK RESOLUTION ON METHOD: AUTHOR EXPDTA X-RAY DIFFRACTION JRNL AUTH R.A.REYNOLDS,A.W.YEM,C.L.WOLFE,M.R.DEIBEL JR., JRNL AUTH 2 C.G.CHIDESTER,K.D.WATENPAUGH JRNL TITL CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF JRNL TITL 2 CDC25B REQUIRED FOR G2/M PHASE TRANSITION OF THE JRNL TITL 3 CELL CYCLE JRNL REF J.MOL.BIOL. V. 293 559 1999 JRNL REFN ASTM JMOBAK UK ISSN 0022-2836 RESOLUTION 1.91 ANGSTROMS.

Sequence in PIR format:

>P1;1qb0A structureX:1qb0A: 374 :A: 551 :A:m-phase inducer phosphatase 2 (cdc25b):homo sapiens: 9.99: 9.99 DHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERD AESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFC EPQDYRPMNHEAFKDELKTFRLKTRSWA*

View SSTRUC file for 1qb0A

Rasmol View of 1qb0A