HEADER    TRANSFERASE                             
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: GLUTATHIONE S-TRANSFERASE;                       
COMPND   3 CHAIN: A, B;                                               
COMPND   4 SYNONYM: GST, HGSTP1-1[V104];                              
COMPND   5 EC: 2.5.1.18;                                              
COMPND   6 ENGINEERED: YES;                                           
COMPND   7 MUTATION: VAL 104 VARIANT;                                 
COMPND   8 BIOLOGICAL_UNIT: ACTIVE AS A DIMER;                        
COMPND   9 OTHER_DETAILS: HGSTP1-1[V104] AND HGSTP1-1[I104] ARE       
COMPND  10 NATURALLY OCCURRING VARIANTS OF HGSTP1-1 OBTAINED BY       
COMPND  11 SITE-DIRECTED MUTAGENESIS                                  
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE   3 ORGANISM_COMMON: HUMAN;                                    
SOURCE   4 ORGAN: PLACENTA;                                           
SOURCE   5 CELLULAR_LOCATION: CYTOPLASM;                              
SOURCE   6 GENE: GTP_HUMAN;                                           
SOURCE   7 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                       
SOURCE   8 EXPRESSION_SYSTEM_STRAIN: BL21 (DE3) PLYSS                 
RESOLUTION  SOURCE               : NULL                       
AUTHOR    X.JI                                                        
RESOLUTION     : FUREY                                        
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   X.JI,M.TORDOVA,R.O'DONNELL,J.F.PARSONS,J.B.HAYDEN, 
JRNL        AUTH 2 G.L.GILLILAND,P.ZIMNIAK                            
JRNL        TITL   STRUCTURE AND FUNCTION OF THE XENOBIOTIC           
JRNL        TITL 2 SUBSTRATE-BINDING SITE AND LOCATION OF A POTENTIAL 
JRNL        TITL 3 NON-SUBSTRATE-BINDING SITE IN A CLASS PI           
JRNL        TITL 4 GLUTATHIONE S-TRANSFERASE                          
JRNL        REF    BIOCHEMISTRY                  V.  36  9690 1997    
JRNL        REFN   ASTM BICHAW  US ISSN 0006-2960                 0033
RESOLUTION   1.80 ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1pgtA
 structureX:1pgtA:   0 :A: 209 :A:glutathione s-transferase:homo sapiens: 9.99: 9.99
 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGR
 TLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQIS
 FADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ*




 View SSTRUC file for 1pgtA 
 Rasmol View of  1pgtA