HEADER    TOXIN                                   
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: PERFRINGOLYSIN O;                                
COMPND   3 CHAIN: NULL;                                               
COMPND   4 SYNONYM: PFO;                                              
COMPND   5 ENGINEERED: YES                                            
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: CLOSTRIDIUM PERFRINGENS;              
SOURCE   3 CELLULAR_LOCATION: CYTOPLASM;                              
SOURCE   4 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                       
SOURCE   5 OTHER_DETAILS: SECRETED AS A MONOMER, FORMS MEMBRANE-BOUND 
SOURCE   6 OLIGOMERS                                                  
RESOLUTION  SOURCE               : PHOTON FACTORY             
AUTHOR    J.ROSSJOHN,M.W.PARKER                                       
RESOLUTION     : BRUNGER                                      
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   J.ROSSJOHN,S.C.FEIL,W.J.MCKINSTRY,R.K.TWETEN,      
JRNL        AUTH 2 M.W.PARKER                                         
JRNL        TITL   STRUCTURE OF A CHOLESTEROL-BINDING, THIOL-ACTIVATED
JRNL        TITL 2 CYTOLYSIN AND A MODEL OF ITS MEMBRANE FORM         
JRNL        REF    CELL(CAMBRIDGE,MASS.)         V.  89   685 1997    
JRNL        REFN   ASTM CELLB5  US ISSN 0092-8674                 0998
RESOLUTION   2.2  ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1pfo-
 structureX:1pfo-:  30 : : 500 : :perfringolysin o:clostridium perfringens: 9.99: 9.99
 DITDKNQSIDSGISSLSYNRNEVLASNGDKIESFVPKEGKKAGNKFIVVERQKRSLTTSPVDISIIDSVNDRTYP
 GALQLADKALVENRPTILMVKRKPININIDLPGLKGENSIKVDDPTYGKVSGAIDELVSKWNEKYSSTHTLPART
 QYSESMVYSKSQISSALNVNAKVLENSLGVDFNAVANNEKKVMILAYKQIFYTVSADLPKNPSDLFDDSVTFNDL
 KQKGVSNEAPPLMVSNVAYGRTIYVKLETTSSSKDVQAAFKALIKNTDIKNSQQYKDIYENSSFTAVVLGGDAQE
 HNKVVTKDFDEIRKVIKDNATFSTKNPAYPISYTSVFLKDNSVAAVHNKTDYIETTSTEYSKGKINLDHSGAYVA
 QFEVAWDEVSYDKEGNEVLTHKTWDGNYQDKTAHYSTVIPLEANARNIRIKARECTGLAWEWWRDVISEYDVPLT
 NNINVSIWGTTLYPGSSITYN*




 View SSTRUC file for 1pfo- 
 Rasmol View of  1pfo-