HEADER METALLOPROTEASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: COLLAGENASE-3; COMPND 3 CHAIN: NULL; COMPND 4 FRAGMENT: C-TERMINAL HEMOPEXIN-LIKE DOMAIN; COMPND 5 SYNONYM: MMP-13; COMPND 6 EC: 3.4.24.-; COMPND 7 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 TISSUE: BREAST CANCER; SOURCE 5 EXPRESSION_SYSTEM: STABLY TRANSFECTED NSO MOUSE MYELOMA; SOURCE 6 EXPRESSION_SYSTEM_CELL: 1PEX CELLS; SOURCE 7 EXPRESSION_SYSTEM_ORGANELLE: PURIFIED FROM SERUM FREE SOURCE 8 CONDITIONED CELL CULTURE MEDIUM RESOLUTION SOURCE : NULL AUTHOR F.X.GOMIS-RUTH,U.GOHLKE,M.BETZ,V.KNAUPER,G.MURPHY, AUTHOR 2 C.LOPEZ-OTIN,W.BODE RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION JRNL AUTH F.X.GOMIS-RUTH,U.GOHLKE,M.BETZ,V.KNAUPER, JRNL AUTH 2 G.MURPHY,C.LOPEZ-OTIN,W.BODE JRNL TITL THE HELPING HAND OF COLLAGENASE-3 (MMP-13) : 2.7 A JRNL TITL 2 CRYSTAL STRUCTURE OF ITS C-TERMINAL HAEMOPEXIN-LIKE JRNL TITL 3 DOMAIN JRNL REF TO BE PUBLISHED JRNL REFN 0353 RESOLUTION 2.7 ANGSTROMS.

Sequence in PIR format:

>P1;1pex- structureX:1pex-: 274 : : 466 : :collagenase-3:homo sapiens: 9.99: 9.99 TPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKF WALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGD KVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC*

View SSTRUC file for 1pex-

Rasmol View of 1pex-