HEADER LIPID BINDING PROTEIN COMPND MOL_ID: 1; COMPND 2 MOLECULE: APOLIPOPROTEIN E; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RECEPTOR BINDING DOMAIN; COMPND 5 SYNONYM: APOE3; COMPND 6 ENGINEERED: YES; COMPND 7 OTHER_DETAILS: SELENOMETHIONINE MUTANT USED IN MAD PHASING COMPND 8 EXPERIMENT SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 STRAIN: BL21, B834(DE)MET-; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: BL21, B834(DE)MET-; SOURCE 8 EXPRESSION_SYSTEM_PLASMID: PET RESOLUTION SOURCE : ROTATING ANODE AUTHOR B.RUPP,B.W.SEGELKE RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION JRNL AUTH B.W.SEGELKE,M.FORSTNER,M.KNAPP,S.TRAKHANOV, JRNL AUTH 2 S.PARKIN,Y.NEWHOUSE,H.D.BELLAMY,K.H.WEISGRABER, JRNL AUTH 3 B.RUPP JRNL TITL CONFORMATIONAL FLEXIBILITY IN THE APOLIPOPROTEIN E JRNL TITL 2 AMINO-TERMINAL DOMAIN STRUCTURE DETERMINED FROM JRNL TITL 3 THREE NEW CRYSTAL FORMS: IMPLICATION FOR LIPID JRNL TITL 4 BINDING JRNL REF PROTEIN SCI. V. 9 886 2000 JRNL REFN ASTM PRCIEI US ISSN 0961-8368 RESOLUTION 1.73 ANGSTROMS.

Sequence in PIR format:

>P1;1or3A structureX:1or3A: 22 :A: 164 :A:apolipoprotein e:homo sapiens: 9.99: 9.99 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT/ARLSKELQAAQA RLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQA*

View SSTRUC file for 1or3A

Rasmol View of 1or3A