HEADER    COMPLEX (HYDROLASE/INHIBITOR)           
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: CATHEPSIN K;                                     
COMPND   3 CHAIN: A;                                                  
COMPND   4 SYNONYM: CATHEPSIN O2;                                     
COMPND   5 EC: 3.4.22.38;                                             
COMPND   6 ENGINEERED: CDNA;                                          
COMPND   7 BIOLOGICAL_UNIT: MONOMER;                                  
COMPND   8 MOL_ID: 2;                                                 
COMPND   9 MOLECULE: INHIBITOR APC3328;                               
COMPND  10 CHAIN: B;                                                  
COMPND  11 ENGINEERED: YES                                            
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE   3 ORGANISM_COMMON: HUMAN;                                    
SOURCE   4 EXPRESSION_SYSTEM: PICHIA PASTORIS;                        
SOURCE   5 EXPRESSION_SYSTEM_CELL_LINE: GS 115;                       
SOURCE   6 MOL_ID: 2;                                                 
SOURCE   7 SYNTHETIC: YES                                             
RESOLUTION  SOURCE               : NULL                       
AUTHOR    M.E.MCGRATH                                                 
RESOLUTION     : BRUNGER                                      
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   M.E.MCGRATH,J.L.KLAUS,M.G.BARNES,D.BROMME          
JRNL        TITL   CRYSTAL STRUCTURE OF HUMAN CATHEPSIN K COMPLEXED   
JRNL        TITL 2 WITH A POTENT INHIBITOR                            
JRNL        REF    NAT.STRUCT.BIOL.              V.   4   105 1997    
JRNL        REFN   ASTM NSBIEW  US ISSN 1072-8368                 2024
RESOLUTION   1.8  ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1memA
 structureX:1memA:   1 :A: 211 :A:inhibitor apc3328:homo sapiens: 9.99: 9.99
 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYV
 QKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVY
 YDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM*




 View SSTRUC file for 1memA 
 Rasmol View of  1memA