HEADER REPLICATION COMPND MOL_ID: 1; COMPND 2 MOLECULE: REPLICASE; COMPND 3 CHAIN: A, B, C, D, E, F; COMPND 4 FRAGMENT: TGEV MAIN PROTEINASE; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: TRANSMISSIBLE GASTROENTERITIS VIRUS; SOURCE 3 ORGANISM_COMMON: VIRUSES; SOURCE 4 GENE: ORF1A; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: TB1; SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PMAL-C2 RESOLUTION SOURCE : EMBL/DESY, HAMBURG ; ELETTR AUTHOR K.ANAND,G.J.PALM,J.R.MESTERS,S.G.SIDDELL,J.ZIEBUHR, AUTHOR 2 R.HILGENFELD RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION JRNL AUTH K.ANAND,G.J.PALM,J.R.MESTERS,S.G.SIDDELL,J.ZIEBUHR, JRNL AUTH 2 R.HILGENFELD JRNL TITL STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS JRNL TITL 2 COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA JRNL TITL 3 ALPHA-HELICAL DOMAIN JRNL REF EMBO J. V. 21 3213 2002 JRNL REFN ASTM EMJODG UK ISSN 0261-4189 RESOLUTION 1.96 ANGSTROMS.

Sequence in PIR format:

>P1;1lvoA structureX:1lvoA: 1 :A: 299 :A:replicase:transmissible gastroenteritis viru: 9.99: 9.99 SGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDTTRVINYENEMSSVRLHNFSVSKNNVFLG VVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYV LENGILYFVYMHHLELGNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMS LESYNTWAKTNSFTELSSTDAFSMLAAKTGQSVEKLLDSIVRLNKGFGGRTILSYGSLCDEFTPTEVIRQMYGV*

View SSTRUC file for 1lvoA

Rasmol View of 1lvoA