HEADER SIGNALING PROTEIN COMPND MOL_ID: 1; COMPND 2 MOLECULE: SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM COMPND 3 CHANNEL PROTEIN 2; COMPND 4 CHAIN: A; COMPND 5 FRAGMENT: CYTOPLASMIC CALMODULIN BINDING DOMAIN (CAMBD); COMPND 6 SYNONYM: CALCIUM-ACTIVATED POTASSIUM CHANNEL RSK2; SK2; COMPND 7 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; SOURCE 3 ORGANISM_COMMON: RAT; SOURCE 4 GENE: SK2 (KCNN2); SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: BL21(DE3); SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PET23B AUTHOR R.WISSMANN,W.BILDL,H.NEUMANN,A.F.RIVARD,N.KLOECKER,D.WEITZ, AUTHOR 2 U.SCHULTE,J.P.ADELMAN,D.BENTROP,B.FAKLER RESOLUTION : MUMENTHALER, GUENTERT EXPDTA NMR, 23 STRUCTURES REVDAT 2 08-FEB-02 1KKD 1 JRNL JRNL AUTH R.WISSMANN,W.BILDL,H.NEUMANN,A.F.RIVARD,N.KLOECKER, JRNL AUTH 2 D.WEITZ,U.SCHULTE,J.P.ADELMAN,D.BENTROP,B.FAKLER JRNL TITL A HELICAL REGION IN THE C-TERMINUS OF JRNL TITL 2 SMALL-CONDUCTANCE CA2+-ACTIVATED K+ CHANNELS JRNL TITL 3 CONTROLS ASSEMBLY WITH APO-CALMODULIN JRNL REF J.BIOL.CHEM. V. 277 4558 2002 JRNL REFN ASTM JBCHA3 US ISSN 0021-9258 RESOLUTION NOT APPLICABLE.

Sequence in PIR format:

>P1;1kkdA structureX:1kkdA: 1 :A: 92 :A:small conductance calcium-activated potassium:rattus norvegicus: 9.99: 9.99 RKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQ RKLNDQANTLVDLAKTQ*

View SSTRUC file for 1kkdA

Rasmol View of 1kkdA