HEADER SIGNALING PROTEIN/SIGNALING ACTIVATOR COMPND MOL_ID: 1; COMPND 2 MOLECULE: GTP-BINDING NUCLEAR PROTEIN RAN; COMPND 3 CHAIN: A, D, G, J; COMPND 4 SYNONYM: RAN, TC4, RAN GTPASE, ANDROGEN RECEPTOR- COMPND 5 ASSOCIATED PROTEIN 24; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN; COMPND 9 CHAIN: B, E, H, K; COMPND 10 SYNONYM: RANBP1, RAN BINDING PROTEIN 1; COMPND 11 ENGINEERED: YES; COMPND 12 MUTATION: YES; COMPND 13 MOL_ID: 3; COMPND 14 MOLECULE: RAN GTPASE ACTIVATING PROTEIN 1; COMPND 15 CHAIN: C, F, I, L; COMPND 16 SYNONYM: RANGAP, PROTEIN RNA1; COMPND 17 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 5 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 6 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 7 EXPRESSION_SYSTEM_PLASMID: PET3D; SOURCE 8 MOL_ID: 2; SOURCE 9 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 10 ORGANISM_COMMON: HUMAN; SOURCE 11 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 12 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 13 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 14 EXPRESSION_SYSTEM_PLASMID: PGEX; SOURCE 15 MOL_ID: 3; SOURCE 16 ORGANISM_SCIENTIFIC: SCHIZOSACCHAROMYCES POMBE; SOURCE 17 ORGANISM_COMMON: FISSION YEAST; SOURCE 18 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 19 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 20 EXPRESSION_SYSTEM_STRAIN: B834; SOURCE 21 EXPRESSION_SYSTEM_PLASMID: PET3D RESOLUTION SOURCE : ESRF AUTHOR M.J.SEEWALD,C.KOERNER,A.WITTINGHOFER,I.R.VETTER RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION JRNL AUTH M.J.SEEWALD,C.KOERNER,A.WITTINGHOFER,I.R.VETTER JRNL TITL RANGAP MEDIATES GTP HYDROLYSIS WITHOUT AN ARGININE JRNL TITL 2 FINGER JRNL REF NATURE V. 415 662 2002 JRNL REFN ASTM NATUAS UK ISSN 0028-0836 RESOLUTION 2.70 ANGSTROMS.

Sequence in PIR format:

>P1;1k5dB structureX:1k5dB: 22 :B: 167 :B:ran gtpase activating protein 1:schizosaccharomyces pombe: 9.99: 9.99 NHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGAIRLLMRRDKTL KICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREK*

View SSTRUC file for 1k5dB

Rasmol View of 1k5dB