HEADER    HYDROLASE                               
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: DIPEPTYDIL-PEPTIDASE I EXCLUSION DOMAIN;         
COMPND   3 CHAIN: A;                                                  
COMPND   4 SYNONYM: DPPI, CATHEPSIN C, RESIDUAL PROPART;              
COMPND   5 EC: 3.4.14.1;                                              
COMPND   6 ENGINEERED: YES;                                           
COMPND   7 MOL_ID: 2;                                                 
COMPND   8 MOLECULE: DIPEPTYDIL-PEPTIDASE I LIGHT CHAIN;              
COMPND   9 CHAIN: B;                                                  
COMPND  10 SYNONYM: DPPI, CATHEPSIN C, BETA CHAIN;                    
COMPND  11 EC: 3.4.14.1;                                              
COMPND  12 ENGINEERED: YES;                                           
COMPND  13 MOL_ID: 3;                                                 
COMPND  14 MOLECULE: DIPEPTYDIL-PEPTIDASE I HEAVY CHAIN;              
COMPND  15 CHAIN: C;                                                  
COMPND  16 SYNONYM: DPPI, CATHEPSIN C, ALPHA CHAIN;                   
COMPND  17 EC: 3.4.14.1;                                              
COMPND  18 ENGINEERED: YES                                            
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE   3 ORGANISM_COMMON: HUMAN;                                    
SOURCE   4 EXPRESSION_SYSTEM_CELL_LINE: HIGH FIVE;                    
SOURCE   5 EXPRESSION_SYSTEM_CELL: INSECT CELL(INVITROGEN);           
SOURCE   6 EXPRESSION_SYSTEM_VECTOR_TYPE: BACULOVIRUS;                
SOURCE   7 EXPRESSION_SYSTEM_VECTOR: PVL1393;                         
SOURCE   8 MOL_ID: 2;                                                 
SOURCE   9 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE  10 ORGANISM_COMMON: HUMAN;                                    
SOURCE  11 EXPRESSION_SYSTEM_CELL_LINE: HIGH FIVE;                    
SOURCE  12 EXPRESSION_SYSTEM_CELL: INSECT CELL(INVITROGEN);           
SOURCE  13 EXPRESSION_SYSTEM_VECTOR_TYPE: BACULOVIRUS;                
SOURCE  14 EXPRESSION_SYSTEM_VECTOR: PVL1393;                         
SOURCE  15 MOL_ID: 3;                                                 
SOURCE  16 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE  17 ORGANISM_COMMON: HUMAN;                                    
SOURCE  18 EXPRESSION_SYSTEM_CELL_LINE: HIGH FIVE;                    
SOURCE  19 EXPRESSION_SYSTEM_CELL: INSECT CELL(INVITROGEN);           
SOURCE  20 EXPRESSION_SYSTEM_VECTOR_TYPE: BACULOVIRUS;                
SOURCE  21 EXPRESSION_SYSTEM_VECTOR: PVL1393                          
RESOLUTION  SOURCE               : ELETTRA                    
AUTHOR    D.TURK,V.JANJIC,I.STERN,M.PODOBNIK,D.LAMBA,S.W.DAHL,        
AUTHOR   2 C.LAURITZEN,J.PEDERSEN,V.TURK,B.TURK                       
RESOLUTION     : TURK                                         
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   D.TURK,V.JANJIC,I.STERN,M.PODOBNIK,D.LAMBA,        
JRNL        AUTH 2 S.W.DAHL,C.LAURITZEN,J.PEDERSEN,V.TURK,B.TURK      
JRNL        TITL   STRUCTURE OF HUMAN DIPEPTIDYL PEPTIDASE I          
JRNL        TITL 2 (CATHEPSIN C): EXCLUSION DOMAIN ADDED TO AN        
JRNL        TITL 3 ENDOPEPTIDASE FRAMEWORK CREATES THE MACHINE FOR    
JRNL        TITL 4 ACTIVATION OF GRANULAR SERINE PROTEASES            
JRNL        REF    EMBO J.                       V.  20  6570 2001    
JRNL        REFN   ASTM EMJODG  UK ISSN 0261-4189                     
RESOLUTION   2.15 ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1k3bA
 structureX:1k3bA:   1 :A: 119 :A:dipeptydil-peptidase i heavy chain:homo sapiens: 9.99: 9.99
 DTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDY
 KWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVG*




 View SSTRUC file for 1k3bA 
 Rasmol View of  1k3bA