HEADER    BLOOD CLOTTING                          
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: TRYPSIN INHIBITOR;                               
COMPND   3 CHAIN: A;                                                  
COMPND   4 ENGINEERED: YES;                                           
COMPND   5 MUTATION: YES                                              
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: BOS TAURUS;                           
SOURCE   3 ORGANISM_COMMON: BOVINE;                                   
SOURCE   4 ORGAN: PANCREAS;                                           
SOURCE   5 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                       
SOURCE   6 EXPRESSION_SYSTEM_COMMON: BACTERIA;                        
SOURCE   7 EXPRESSION_SYSTEM_STRAIN: HB101;                           
SOURCE   8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                    
SOURCE   9 EXPRESSION_SYSTEM_PLASMID: PTI103                          
AUTHOR    J.L.BATTISTE,R.LI,C.WOODWARD                                
RESOLUTION     : BRUNGER, A. T.                               
EXPDTA    NMR, 23 STRUCTURES                                          
REVDAT   2   27-FEB-02 1JV8    1       JRNL   REMARK                  
JRNL        AUTH   J.L.BATTISTE,R.LI,C.WOODWARD                       
JRNL        TITL   A HIGHLY DESTABILIZING MUTATION, G37A, OF THE      
JRNL        TITL 2 BOVINE PANCREATIC TRYPSIN INHIBITOR RETAINS THE    
JRNL        TITL 3 AVERAGE NATIVE CONFORMATION BUT GREATLY INCREASES  
JRNL        TITL 4 LOCAL FLEXIBILITY.                                 
JRNL        REF    BIOCHEMISTRY                  V.  41  2237 2002    
JRNL        REFN   ASTM BICHAW  US ISSN 0006-2960                     
RESOLUTION   NOT APPLICABLE.                                  



 Sequence in PIR format: 
>P1;1jv8A
 structureX:1jv8A:   1 :A:  58 :A:trypsin inhibitor:bos taurus: 9.99: 9.99
 RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGACRAKRNNFKSAEDCMRTCGGA*




 View SSTRUC file for 1jv8A 
 Rasmol View of  1jv8A