HEADER CARBOXYPEPTIDASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: HUMAN PROTECTIVE PROTEIN; COMPND 3 CHAIN: A, B; COMPND 4 SYNONYM: PROTECTIVE PROTEIN/CATHEPSIN A, COMPND 5 CARBOXYPEPTIDASE L; COMPND 6 EC: 3.4.16.5; COMPND 7 ENGINEERED: YES; COMPND 8 BIOLOGICAL_UNIT: HETERODIMER SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: SF21 INSECT CELLS; SOURCE 5 EXPRESSION_SYSTEM_GENE: HUPP54; SOURCE 6 OTHER_DETAILS: BACULOVIRUS MEDIATED OVER-EXPRESSION. SEE SOURCE 7 BONTEN ET AL. 1995, J.B.C. 270, P. 26441-26445 RESOLUTION SOURCE : SSRL AUTHOR G.RUDENKO,E.BONTEN,A.D'AZZO,W.G.J.HOL RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION JRNL AUTH G.RUDENKO,E.BONTEN,A.D'AZZO,W.G.HOL JRNL TITL THREE-DIMENSIONAL STRUCTURE OF THE HUMAN JRNL TITL 2 'PROTECTIVE PROTEIN': STRUCTURE OF THE PRECURSOR JRNL TITL 3 FORM SUGGESTS A COMPLEX ACTIVATION MECHANISM JRNL REF STRUCTURE (LONDON) V. 3 1249 1995 JRNL REFN ASTM STRUE6 UK ISSN 0969-2126 2005 RESOLUTION 2.2 ANGSTROMS.
Sequence in PIR format:
>P1;1ivyA structureX:1ivyA: 1 :A: 452 :A:human protective protein:homo sapiens: 9.99: 9.99 APDQDEIQRLPGLAKQPSFRQYSGYLKSSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLV QPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGES YAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKD LECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMAC NFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQ PY*
View SSTRUC file for 1ivyA
Rasmol View of 1ivyA