HEADER LIPID TRANSPORT COMPND MOL_ID: 1; COMPND 2 MOLECULE: LOW-DENSITY LIPOPROTEIN RECEPTOR; COMPND 3 CHAIN: A, B; COMPND 4 FRAGMENT: YWTD-E3 DOMAIN; COMPND 5 SYNONYM: LDL RECEPTOR; COMPND 6 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 GENE: LDLR; SOURCE 5 EXPRESSION_SYSTEM: CRICETULUS GRISEUS; SOURCE 6 EXPRESSION_SYSTEM_COMMON: CHINESE HAMSTER; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: CHOLEC; SOURCE 8 EXPRESSION_SYSTEM_ORGAN: OVARY; SOURCE 9 EXPRESSION_SYSTEM_CELL: CHO; SOURCE 10 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 11 EXPRESSION_SYSTEM_PLASMID: PEF1/V5-HIS RESOLUTION SOURCE : CHESS ; ROTATING ANODE AUTHOR H.JEON,W.MENG,J.TAKAGI,M.J.ECK,T.A.SPRINGER,S.C.BLACKLOW RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION REVDAT 2 30-MAY-01 1IJQ 1 JRNL JRNL AUTH H.JEON,W.MENG,J.TAKAGI,M.J.ECK,T.A.SPRINGER, JRNL AUTH 2 S.C.BLACKLOW JRNL TITL IMPLICATIONS FOR FAMILIAL HYPERCHOLESTEROLEMIA JRNL TITL 2 FROM STRUCTURE OF THE LDL RECEPTOR YWTD-EGF DOMAIN JRNL TITL 3 PAIR JRNL REF NAT.STRUCT.BIOL. V. 8 499 2001 JRNL REFN ASTM NSBIEW US ISSN 1072-8368 RESOLUTION 1.50 ANGSTROMS.
Sequence in PIR format:
>P1;1ijqA structureX:1ijqA: 377 :A: 692 :A:low-density lipoprotein receptor:homo sapiens: 9.99: 9.99 IAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQL/YDTVISRDIQAPDGL AVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYS LVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIF SANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLL ARDMRSCLT*
View SSTRUC file for 1ijqA
Rasmol View of 1ijqA