HEADER CYTOKINE/RECEPTOR COMPND MOL_ID: 1; COMPND 2 MOLECULE: INTERLEUKIN-4; COMPND 3 CHAIN: A; COMPND 4 ENGINEERED: YES; COMPND 5 MOL_ID: 2; COMPND 6 MOLECULE: INTERLEUKIN-4 RECEPTOR ALPHA CHAIN; COMPND 7 CHAIN: B; COMPND 8 FRAGMENT: EXTRACELLULAR DOMAIN; COMPND 9 ENGINEERED: YES; COMPND 10 MUTATION: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 5 OTHER_DETAILS: RECOMBINANT; SOURCE 6 MOL_ID: 2; SOURCE 7 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 8 ORGANISM_COMMON: HUMAN; SOURCE 9 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 10 OTHER_DETAILS: RECOMBINANT RESOLUTION SOURCE : DESY-EMBL,HAMBUR AUTHOR T.HAGE,W.SEBALD,P.REINEMER RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION JRNL AUTH T.HAGE,W.SEBALD,P.REINEMER JRNL TITL CRYSTAL STRUCTURE OF THE INTERLEUKIN-4 / RECEPTOR JRNL TITL 2 ALPHA CHAIN COMPLEX REVEALS A MOSAIC BINDING JRNL TITL 3 INTERFACE JRNL REF CELL (CAMBRIDGE,MASS.) V. 97 271 1999 JRNL REFN ASTM CELLB5 US ISSN 0092-8674 RESOLUTION 2.30 ANGSTROMS.
Sequence in PIR format:
>P1;1iarB structureX:1iarB: 1 :B: 197 :B:interleukin-4 receptor alpha chain:homo sapiens: 9.99: 9.99 FKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYT LDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVH/DTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVT YLEPSLRIAA/GISYRARVRAWAQAYNTTWSEWSPSTKWH*
View SSTRUC file for 1iarB
Rasmol View of 1iarB