HEADER OXIDOREDUCTASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: L-LACTATE/MALATE DEHYDROGENASE; COMPND 3 CHAIN: A; COMPND 4 EC: 1.1.1.27; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: METHANOCOCCUS JANNASCHII; SOURCE 3 ORGANISM_COMMON: ARCHAEA; SOURCE 4 GENE: MJ0490; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: C41(DE3); SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PET22B RESOLUTION SOURCE : ROTATING ANODE AUTHOR B.I.LEE,C.CHANG,S.-J.CHO,S.W.SUH RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION JRNL AUTH B.I.LEE,C.CHANG,S.-J.CHO,S.H.EOM,K.K.KIM,Y.G.YU, JRNL AUTH 2 S.W.SUH JRNL TITL CRYSTAL STRUCTURE OF THE MJ0490 GENE PRODUCT OF JRNL TITL 2 THE HYPERTHERMOPHILIC ARCHAEBACTERIUM JRNL TITL 3 METHANOCOCCUS JANNASCHII,A NOVEL MEMBER OF THE JRNL TITL 4 LACTATE/MALATE FAMILY OF DEHYDROGENASES JRNL REF J.MOL.BIOL. V. 307 1351 2001 JRNL REFN ASTM JMOBAK UK ISSN 0022-2836 RESOLUTION 1.90 ANGSTROMS.

Sequence in PIR format:

>P1;1hyeA structureX:1hyeA: 1 :A: 313 :A:l-lactate/malate dehydrogenase:methanococcus jannaschii: 9.99: 9.99 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDANIYVESDENLRIIDES DVVIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEICDTKIFVITNPVDVMTYKALVDSKFERNQVFGLGTHL DSLRFKVAIAKFFGVHIDEVRTRIIGEHGDSMVPLLSATSIGGIPIQKFERFKELPIDEIIEDVKTKGEQIIR/F GPAAAILNVVRCIVNNEKRLLTLSAYVDGEFDGIRDVCIGVPVKIGRDGIEEVVSIELDKDEIIAFRKSAEIIKK YCEEVKNL*

View SSTRUC file for 1hyeA

Rasmol View of 1hyeA