HEADER HYDROLASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: STROMELYSIN 3; COMPND 3 CHAIN: A, B, C, D, E, F; COMPND 4 SYNONYM: MATRIX METALLOPROTEINASE 11, MMP-11, ST3, SL-3; COMPND 5 EC: 3.4.24.-; COMPND 6 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 3 ORGANISM_COMMON: MOUSE; SOURCE 4 GENE: STRO3 (101-264); SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PET 3B RESOLUTION SOURCE : ESRF AUTHOR A.L.GALL,M.RUFF,R.KANNAN,P.CUNIASSE,A.YIOTAKIS,V.DIVE, AUTHOR 2 M.C.RIO,P.BASSET,D.MORAS RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION JRNL AUTH A.L.GALL,M.RUFF,R.KANNAN,P.CUNIASSE,A.YIOTAKIS, JRNL AUTH 2 V.DIVE,M.C.RIO,P.BASSET,D.MORAS JRNL TITL CRYSTAL STRUCTURE OF THE STROMELYSIN-3 (MMP-11) JRNL TITL 2 CATALYTIC DOMAIN COMPLEXED WITH A PHOSPHINIC JRNL TITL 3 INHIBITOR MIMICKING THE TRANSITION-STATE JRNL REF J.MOL.BIOL. V. 307 577 2001 JRNL REFN ASTM JMOBAK UK ISSN 0022-2836 RESOLUTION 2.60 ANGSTROMS.

Sequence in PIR format:

>P1;1hv5A structureX:1hv5A: 101 :A: 262 :A:stromelysin 3:mus musculus: 9.99: 9.99 MFVLSGGRWEKTDLTYRILRFPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFD GPGGILAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPFYTFRYPLSLS PDDRRGIQHLYG*

View SSTRUC file for 1hv5A

Rasmol View of 1hv5A