HEADER    HYDROLASE                               
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: ALPHA-MANNOSIDASE II;                            
COMPND   3 CHAIN: A;                                                  
COMPND   4 SYNONYM: GOLGI ALPHA-MANNOSIDASE II;                       
COMPND   5 EC: 3.2.1.114;                                             
COMPND   6 ENGINEERED: YES                                            
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: DROSOPHILA MELANOGASTER;              
SOURCE   3 ORGANISM_COMMON: FRUIT FLY;                                
SOURCE   4 EXPRESSION_SYSTEM: DROSOPHILA MELANOGASTER;                
SOURCE   5 EXPRESSION_SYSTEM_COMMON: FRUIT FLY;                       
SOURCE   6 EXPRESSION_SYSTEM_CELL: S2                                 
RESOLUTION  SOURCE               : APS ; APS                  
AUTHOR    J.M.H.VAN DEN ELSEN,D.A.KUNTZ,D.R.ROSE                      
RESOLUTION     : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE-      
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   J.M.H.VAN DEN ELSEN,D.A.KUNTZ,D.R.ROSE             
JRNL        TITL   STRUCTURE OF GOLGI ALPHA-MANNOSIDASE II: A TARGET  
JRNL        TITL 2 FOR INHIBITION OF GROWTH AND METASTASIS OF CANCER  
JRNL        TITL 3 CELLS.                                             
JRNL        REF    EMBO J.                       V.  20  3008 2001    
JRNL        REFN   ASTM EMJODG  UK ISSN 0261-4189                     
RESOLUTION   1.40 ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1htyA
 structureX:1htyA:  31 :A:1044 :A:alpha-mannosidase ii:drosophila melanogaster: 9.99: 9.99
 CQDVVQDVPNVDVQ/LELYDR/SFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYYQH
 DTKHILSNALRHLHDNPE/KFIWAEISYFARFYHDLGENKKLQKSIVKNGQLEFVTGGWV/PDEANSHWRNVLLQ
 LTEGQTWLKQFNVTPTASWAIDPFGHSPT/PYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDT
 ALFTH/PFYSYDIPHTCGPDPKVCCQFDFKR/GSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNV
 LLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYA
 DRSDNYWSGYYTSRPYHKRDRVLHYVRAAE/LSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVD
 YEQRQEALKACQV/QQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVV/HNTLP
 HWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPGLATYVLTISD
 SKPEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFL
 KYGVRSHGDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTI/RGGAPEIRNLVDIGSLDNT
 EIV/RLETHIDSGDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSG/FIEDANTRLTLLTGQPLGGSSLASGELE
 I/QDRRLASDDERGLGQGVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENE
 WIGAQGQFGGDHPSAREDLDVSV/RRLTKSSAKTQRVGYVLHRTNL/QCGTPEEHTQKLDVCHLLPNVARCERTT
 LTFLQNLEHLDG/VAPEVCP/ETAAYVSSHS*




 View SSTRUC file for 1htyA 
 Rasmol View of  1htyA