HEADER HYDROLASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: 92 KDA TYPE IV COLLAGENASE ; COMPND 3 SYNONYM: MMP-9, 92 KDA GELATINASE, GELATINASE B, COMPND 4 MATRIX METALLOPROTEINASE-9; COMPND 5 CHAIN: A, B; COMPND 6 FRAGMENT: CATALYTIC DOMAIN RESIDUES 107-215, 391-443; COMPND 7 EC: 3.4.24.35; COMPND 8 ENGINEERED: YES; COMPND 9 MUTATION: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI RESOLUTION SOURCE : SRS BEAMLINE PX9.6 AUTHOR S.ROWSELL,R.A.PAUPTIT RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS, EXPDTA X-RAY DIFFRACTION JRNL AUTH S.ROWSELL,P.HAWTIN,C.A.MINSHULL,H.JEPSON, JRNL AUTH 2 S.BROCKBANK,D.BARRATT,A.M.SLATER,W.MCPHEAT, JRNL AUTH 3 D.WATERSON,A.HENNEY,R.A.PAUPTIT JRNL TITL CRYSTAL STRUCTURE OF MMP9 IN COMPLEX WITH A REVERSE JRNL TITL 2 HYDROXAMATE INHIBITOR JRNL REF J.MOL.BIOL. V. 319 173 2002 JRNL REFN ASTM JMOBAK UK ISSN 0022-2836 RESOLUTION 2.1 ANGSTROMS.
Sequence in PIR format:
>P1;1gkdA structureX:1gkdA: 110 :A: 443 :A:92 kda type iv collagenase:homo sapiens: 9.99: 9.99 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGK DGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKD DVNGIRHLY*
View SSTRUC file for 1gkdA
Rasmol View of 1gkdA