HEADER    SIGNALING PROTEIN                       
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: PROTEIN-TYROSINE PHOSPHATASE 1C;                 
COMPND   3 CHAIN: A;                                                  
COMPND   4 FRAGMENT: CATALYTIC DOMAIN;                                
COMPND   5 SYNONYM: PTP-1C, HEMATOPOIETIC CELL PROTEIN-TYROSINE       
COMPND   6 PHOSPHATASE, SH-PTP1;                                      
COMPND   7 EC: 3.1.3.48;                                              
COMPND   8 ENGINEERED: YES;                                           
COMPND   9 MUTATION: YES;                                             
COMPND  10 MOL_ID: 2;                                                 
COMPND  11 MOLECULE: PEPTIDE PY469;                                   
COMPND  12 CHAIN: B;                                                  
COMPND  13 ENGINEERED: YES                                            
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE   3 ORGANISM_COMMON: HUMAN;                                    
SOURCE   4 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                       
SOURCE   5 EXPRESSION_SYSTEM_COMMON: BACTERIA;                        
SOURCE   6 MOL_ID: 2;                                                 
SOURCE   7 SYNTHETIC: YES;                                            
SOURCE   8 OTHER_DETAILS: THIS PEPTIDE WAS CHEMICALLY SYNTHESIZED.    
SOURCE   9 THE SEQUENCE OF THIS PEPTIDE OCCURS NATURALLY IN HUMANS    
SOURCE  10 (HOMO SAPIENS)                                             
RESOLUTION  SOURCE               : ROTATING ANODE             
AUTHOR    J.YANG,Z.CHENG,Z.NIU,Z.J.ZHAO,G.W.ZHOU                      
RESOLUTION     : BRUNGER                                      
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   J.YANG,Z.CHENG,Z.NIU,Z.J.ZHAO,G.W.ZHOU             
JRNL        TITL   STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY OF      
JRNL        TITL 2 PROTEIN TYROSINE PHOSPHATASE SHP-1                 
JRNL        REF    J.BIOL.CHEM.                  V. 275  4066 2000    
JRNL        REFN   ASTM JBCHA3  US ISSN 0021-9258                     
RESOLUTION   2.50 ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1fprA
 structureX:1fprA: 245 :A: 528 :A:peptide py469:homo sapiens: 9.99: 9.99
 GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDEN
 AKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKL
 RTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVID
 MLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVL*




 View SSTRUC file for 1fprA 
 Rasmol View of  1fprA