HEADER    PHOSPHOTRANSFERASE                      
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: FGF RECEPTOR 1;                                  
COMPND   3 CHAIN: A, B;                                               
COMPND   4 FRAGMENT: TYROSINE KINASE DOMAIN, HUMAN FGFR1 RESIDUES THAT
COMPND   5 POSSESS PTK ACTIVITY;                                      
COMPND   6 SYNONYM: FGFR1K, FIBROBLAST GROWTH FACTOR RECEPTOR 1;      
COMPND   7 EC: 2.7.1.112;                                             
COMPND   8 ENGINEERED: YES;                                           
COMPND   9 MUTATION: L457V, C488A, C584S                              
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 FRAGMENT: HUMAN FGFR1 RESIDUES 456-765 THAT POSSESSES PTK  
SOURCE   3 ACTIVITY;                                                  
SOURCE   4 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                         
SOURCE   5 ORGANISM_COMMON: HUMAN;                                    
SOURCE   6 CELLULAR_LOCATION: CYTOPLASM;                              
SOURCE   7 EXPRESSION_SYSTEM: BACULOVIRUS/INSECT CELL                 
RESOLUTION  SOURCE               : NSLS                       
AUTHOR    M.MOHAMMADI,J.SCHLESSINGER,S.R.HUBBARD                      
RESOLUTION     : BRUNGER                                      
EXPDTA    X-RAY DIFFRACTION                                           
RESOLUTION   2.0  ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1fgkA
 structureX:1fgkA: 464 :A: 762 :A:fgf receptor 1:homo sapiens: 9.99: 9.99
 ELPEDPRWELPRDRLVLGKPLG/QVVLAEAIGL/PNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNII
 NLLGACTQDGPLYVIVEYASKGNLREYLQARRPP/EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLV
 TEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV
 EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS*




 View SSTRUC file for 1fgkA 
 Rasmol View of  1fgkA