HEADER OXIDOREDUCTASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: L-3-HYDROXYACYL-COA DEHYDROGENASE; COMPND 3 CHAIN: A, B; COMPND 4 SYNONYM: HCDH; COMPND 5 EC: 1.1.1.35; COMPND 6 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGAN: HEART; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_COMMON: BACTERIA; SOURCE 7 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 8 EXPRESSION_SYSTEM_PLASMID: PET28 RESOLUTION SOURCE : ROTATING ANODE AUTHOR J.J.BARYCKI,L.K.O'BRIEN,A.W.STRAUSS,L.J.BANASZAK RESOLUTION : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- EXPDTA X-RAY DIFFRACTION JRNL AUTH J.J.BARYCKI,L.K.O'BRIEN,A.W.STRAUSS,L.J.BANASZAK JRNL TITL SEQUESTRATION OF THE ACTIVE SITE BY INTERDOMAIN JRNL TITL 2 SHIFTING: CRYSTALLOGRAPHIC AND SPECTROSCOPIC JRNL TITL 3 EVIDENCE FOR DISTINCT CONFORMATIONS OF JRNL TITL 4 L-3-HYDROXYACYL-COA DEHYDROGENASE JRNL REF J.BIOL.CHEM. V. 275 27186 2000 JRNL REFN ASTM JBCHA3 US ISSN 0021-9258 RESOLUTION 1.80 ANGSTROMS.

Sequence in PIR format:

>P1;1f0yA structureX:1f0yA: 12 :A: 302 :A:l-3-hydroxyacyl-coa dehydrogenase:homo sapiens: 9.99: 9.99 KIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLS TIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFN PVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAM KLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK*

View SSTRUC file for 1f0yA

Rasmol View of 1f0yA