HEADER ISOMERASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: UDP-GALACTOSE 4-EPIMERASE; COMPND 3 CHAIN: A, B; COMPND 4 EC: 5.1.3.2; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 TISSUE: FORESKIN; SOURCE 5 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE; SOURCE 6 EXPRESSION_SYSTEM_COMMON: YEAST RESOLUTION SOURCE : APS AUTHOR J.B.THODEN,T.M.WOHLERS,J.L.FRIDOVICH-KEIL,H.M.HOLDEN RESOLUTION : TRONRUD,TEN EYCK,MATTHEWS EXPDTA X-RAY DIFFRACTION JRNL AUTH J.B.THODEN,T.M.WOHLERS,J.L.FRIDOVICH-KEIL, JRNL AUTH 2 H.M.HOLDEN JRNL TITL CRYSTALLOGRAPHIC EVIDENCE FOR TYR157 FUNCTIONING JRNL TITL 2 AS THE ACTIVE SITE BASE IN HUMAN UDP-GALACTOSE JRNL TITL 3 4-EPIMERASE JRNL REF BIOCHEMISTRY V. 39 5691 2000 JRNL REFN ASTM BICHAW US ISSN 0006-2960 RESOLUTION 1.50 ANGSTROMS.

Sequence in PIR format:

>P1;1ek6A structureX:1ek6A: 1 :A: 346 :A:udp-galactose 4-epimerase:homo sapiens: 9.99: 9.99 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQR LFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPT GGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNV FGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGT*

View SSTRUC file for 1ek6A

Rasmol View of 1ek6A