HEADER APOPTOSIS COMPND MOL_ID: 1; COMPND 2 MOLECULE: FADD PROTEIN; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: DEATH DOMAIN RESIDUES 93-192; COMPND 5 SYNONYM: FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN ; COMPND 6 ENGINEERED: YES; COMPND 7 MUTATION: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 5 EXPRESSION_SYSTEM_STRAIN: BL21 DE3; SOURCE 6 EXPRESSION_SYSTEM_VECTOR_TYPE: T7; SOURCE 7 EXPRESSION_SYSTEM_PLASMID: PET14B; SOURCE 8 OTHER_DETAILS: PCR CLONING INTO N-TERMINAL 6*HIS TAG SOURCE 9 THROMBIN-CLEAVABLE FUSION PROTEIN AUTHOR P.C.DRISCOLL,H.BERGLUND,D.OLERENSHAW,N.Q.MCDONALD RESOLUTION : BRUNGER EXPDTA NMR, MINIMIZED AVERAGE STRUCTURE JRNL AUTH H.BERGLUND,D.OLERENSHAW,A.SANKAR,M.FEDERWISCH, JRNL AUTH 2 N.Q.MCDONALD,P.C.DRISCOLL JRNL TITL THE THREE-DIMENSIONAL SOLUTION STRUCTURE AND JRNL TITL 2 DYNAMIC PROPERTIES OF THE HUMAN FADD DEATH DOMAIN JRNL REF J.MOL.BIOL. V. 302 171 2000 JRNL REFN ASTM JMOBAK UK ISSN 0022-2836 RESOLUTION L CITATION ABOVE. RESOLUTION NOT APPLICABLE.

Sequence in PIR format:

>P1;1e3yA structureX:1e3yA: 89 :A: 192 :A:fadd protein:homo sapiens: 9.99: 9.99 GSHMGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVG ALRSCQMNLVADLVQEVQQARDLQNRSGA*

View SSTRUC file for 1e3yA

Rasmol View of 1e3yA