HEADER    HYDROLASE (SERINE ESTERASE)             
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: ACETYLCHOLINESTERASE;                            
COMPND   3 CHAIN: A;                                                  
COMPND   4 EC: 3.1.1.7;                                               
COMPND   5 ENGINEERED: YES                                            
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: DROSOPHILA MELANOGASTER;              
SOURCE   3 ORGANISM_COMMON: FRUIT FLY;                                
SOURCE   4 EXPRESSION_SYSTEM: DROSOPHILA MELANOGASTER;                
SOURCE   5 EXPRESSION_SYSTEM_STRAIN: SCHNEIDER LINE 2;                
SOURCE   6 EXPRESSION_SYSTEM_CELLULAR_LOCATION: SECRETED              
SOURCE   7 (EXTRACELLULAR);                                           
SOURCE   8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID DNA;                
SOURCE   9 EXPRESSION_SYSTEM_PLASMID: S2-SEC 1/3;                     
SOURCE  10 EXPRESSION_SYSTEM_GENE: DMACHE                             
RESOLUTION  SOURCE               : NSLS BEAMLINE X12C         
AUTHOR    M.HAREL,I.SILMAN,J.L.SUSSMAN                                
RESOLUTION     : BRUNGER,ADAMS,CLORE,DELANO,GROS,             
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   M.HAREL,G.KRYGER,T.L.ROSENBERRY,W.D.MALLENDER,     
JRNL        AUTH 2 T.LEWIS,R.J.FLETCHER,J.M.GUSS,I.SILMAN,J.L.SUSSMAN 
JRNL        TITL   THREE-DIMENSIONAL STRUCTURES OF DROSOPHILA         
JRNL        TITL 2 MELANOGASTER ACETYLCHOLINESTERASE AND OF ITS       
JRNL        TITL 3 COMPLEXES WITH TWO POTENT INHIBITORS               
JRNL        REF    PROTEIN SCI.                  V.   9  1063 2000    
JRNL        REFN   ASTM PRCIEI  US ISSN 0961-8368                     
RESOLUTION   2.7  ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1dx4A
 structureX:1dx4A:   3 :A: 573 :A:acetylcholinesterase:drosophila melanogaster: 9.99: 9.99
 DRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATGLSATCVQERYEYFPGF
 SGEEIWNPNTNVSEDCLYINVWAPA/TTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAF
 GFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRG
 MMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPT
 IDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAERE
 AIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIE
 YFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARC
 SFWNDYLPKVRSW*




 View SSTRUC file for 1dx4A 
 Rasmol View of  1dx4A