HEADER HYDROLASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: EPOXIDE HYDROLASE; COMPND 3 CHAIN: A, B; COMPND 4 EC: 3.3.2.3; COMPND 5 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 3 ORGANISM_COMMON: MOUSE; SOURCE 4 ORGAN: LIVER; SOURCE 5 EXPRESSION_SYSTEM_COMMON: INSECT; SOURCE 6 EXPRESSION_SYSTEM_VECTOR: BACCULOVIRUS RESOLUTION SOURCE : CHESS AUTHOR M.A.ARGIRIADI,C.MORISSEAU,B.D.HAMMOCK,D.W.CHRISTIANSON RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION JRNL AUTH M.A.ARGIRIADI,C.MORISSEAU,B.D.HAMMOCK, JRNL AUTH 2 D.W.CHRISTIANSON JRNL TITL DETOXIFICATION OF ENVIRONMENTAL MUTAGENS AND JRNL TITL 2 CARCINOGENS: STRUCTURE-BASED MECHANISM AND JRNL TITL 3 EVOLUTION OF LIVER EPOXIDE HYDROLASE JRNL REF PROC.NAT.ACAD.SCI.USA V. 96 10637 1999 JRNL REFN ASTM PNASA6 US ISSN 0027-8424 RESOLUTION 2.80 ANGSTROMS.
Sequence in PIR format:
>P1;1cr6A structureX:1cr6A: 4 :A: 544 :A:epoxide hydrolase:mus musculus: 9.99: 9.99 RVAAFDLDGVLALPSI/GPTEQLMKGKITFSQW/QIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDG DKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHN TASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALA QAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVAS LNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVN TPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKN MEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTE*
View SSTRUC file for 1cr6A
Rasmol View of 1cr6A