HEADER ASPARTYL PROTEASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: HIV-1 PROTEASE; COMPND 3 CHAIN: A, B; COMPND 4 EC: 3.4.23.16; COMPND 5 ENGINEERED: YES; COMPND 6 MUTATION: C95A SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HUMAN IMMUNODEFICIENCY VIRUS; SOURCE 3 ORGANISM_COMMON: AIDS VIRUS; SOURCE 4 STRAIN: HXB2; SOURCE 5 EXPRESSION_SYSTEM: BL21; SOURCE 6 EXPRESSION_SYSTEM_PLASMID: PET11A AUTHOR T.YAMAZAKI,A.P.HINCK,Y.-X.WANG,L.K.NICHOLSON,D.A.TORCHIA, AUTHOR 2 P.WINGFIELD,S.J.STAHL,J.D.KAUFMAN,C.CHANG,P.J.DOMAILLE, AUTHOR 3 P.Y.S.LAM RESOLUTION : BRUNGER EXPDTA NMR, 28 STRUCTURES JRNL AUTH T.YAMAZAKI,A.P.HINCK,Y.-X.WANG,L.K.NICHOLSON, JRNL AUTH 2 D.A.TORCHIA,P.WINGFIELD,S.J.STAHL,J.D.KAUFMAN, JRNL AUTH 3 C-H.CHANG,P.J.DOMAILLE,P.Y.S.LAM JRNL TITL THREE DIMENSIONAL SOLUTION STRUCTURE OF THE HIV-1 JRNL TITL 2 PROTEASE COMPLEXED WITH DMP323, A NOVEL CYCLIC JRNL TITL 3 UREA-TYPE INHIBITOR, DETERMINED BY NUCLEAR JRNL TITL 4 MAGNETIC RESONANCE SPECTROSCOPY JRNL REF TO BE PUBLISHED JRNL REFN 0353 RESOLUTION NOT APPLICABLE.

Sequence in PIR format:

>P1;1bveA structureX:1bveA: 1 :A: 99 :A:hiv-1 protease:human immunodeficiency virus: 9.99: 9.99 PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTV LVGPTPVNIIGRNLLTQIGATLNF*

View SSTRUC file for 1bveA

Rasmol View of 1bveA