HEADER METHYLTRANSFERASE REVDAT 2 23-MAR-99 1BKPA 1 REMARK HEADER JRNL KEYWDS COMPND MOL_ID: 1; COMPND 2 MOLECULE: THYMIDYLATE SYNTHASE A; COMPND 3 CHAIN: A, B; COMPND 4 EC: 2.1.1.45; COMPND 5 ENGINEERED: YES; COMPND 6 BIOLOGICAL_UNIT: OBLIGATE DIMER SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: BACILLUS SUBTILIS; SOURCE 3 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 4 EXPRESSION_SYSTEM_CELL_LINE: X2913; SOURCE 5 EXPRESSION_SYSTEM_VECTOR: PTRC 99A; SOURCE 6 EXPRESSION_SYSTEM_PLASMID: PTRC-THYA; SOURCE 7 EXPRESSION_SYSTEM_GENE: THYA RESOLUTION SOURCE : NONE AUTHOR T.J.STOUT,U.SCHELLENBERGER,D.V.SANTI,R.M.STROUD RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION REVDAT 2 23-MAR-99 1BKPA 1 REMARK HEADER JRNL KEYWDS JRNL AUTH T.J.STOUT,U.SCHELLENBERGER,D.V.SANTI,R.M.STROUD JRNL TITL CRYSTAL STRUCTURES OF A UNIQUE THERMAL-STABLE JRNL TITL 2 THYMIDYLATE SYNTHASE FROM BACILLUS SUBTILIS JRNL REF BIOCHEMISTRY V. 37 14736 1998 JRNL REFN ASTM BICHAW US ISSN 0006-2960 0033 RESOLUTION 1.7 ANGSTROMS.

Sequence in PIR format:

>P1;1bkpA structureX:1bkpA: 2 :A: 279 :A:thymidylate synthase a:bacillus subtilis: 9.99: 9.99 TQFDKQYNSIIKDIINNGISDEEFDVRTKWDSDGTPAHTLSVISKQMRFDNSEVPILTTKKVAWKTAIKELLWIW QLKSNDVNDLNMMGVHIWDQWKQEDGTIGHAYGFQLGKKNRSLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPD ELDAMALTPCVYETQWYVKHGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNIGDCHVYTR HIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLINYKHGDKLLFEVAV*

View SSTRUC file for 1bkpA

Rasmol View of 1bkpA