HEADER HYDROLASE COMPND MOL_ID: 1; COMPND 2 MOLECULE: ADENOVIRAL PROTEINASE; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: MAIN; COMPND 5 SYNONYM: AVP; COMPND 6 ENGINEERED: YES; COMPND 7 BIOLOGICAL_UNIT: MONOMER; COMPND 8 OTHER_DETAILS: PVIC PEPTIDE COFACTOR DISULFIDE BONDS TO COMPND 9 CYS104 OF AVP; COMPND 10 MOL_ID: 2; COMPND 11 MOLECULE: ADENOVIRAL PROTEINASE; COMPND 12 CHAIN: B; COMPND 13 FRAGMENT: PEPT; COMPND 14 SYNONYM: PVIC; COMPND 15 BIOLOGICAL_UNIT: MONOMER; COMPND 16 OTHER_DETAILS: PVIC PEPTIDE IS CHEMICALLY SYNTHESIZED PVIC COMPND 17 PEPTIDE COFACTOR DISULFIDE BONDS TO CYS104 OF AVP SOURCE MOL_ID: 1; SOURCE 2 FRAGMENT: MAIN; SOURCE 3 ORGANISM_SCIENTIFIC: MASTADENOVIRUS H2; SOURCE 4 ORGANISM_COMMON: HUMAN ADENOVIRUS 2; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_STRAIN: BL21; SOURCE 7 EXPRESSION_SYSTEM_VARIANT: DE3; SOURCE 8 EXPRESSION_SYSTEM_PLASMID: PET 13; SOURCE 9 MOL_ID: 2; SOURCE 10 SYNTHETIC: YES; SOURCE 11 FRAGMENT: PEPT; SOURCE 12 OTHER_DETAILS: CHEMICALLY SYNTHESIZED TO MATCH THE SOURCE 13 C-TERMINAL 11 AMINO ACID OF ADENOVIRAL PRECURSOR PROTEIN SOURCE 14 PVI RESOLUTION SOURCE : NSLS AUTHOR J.DING,W.J.MCGRATH,R.M.SWEET,W.F.MANGEL RESOLUTION : BRUNGER EXPDTA X-RAY DIFFRACTION, SINGLE CRYSTAL JRNL AUTH J.DING,W.J.MCGRATH,R.M.SWEET,W.F.MANGEL JRNL TITL CRYSTAL STRUCTURE OF THE HUMAN ADENOVIRUS JRNL TITL 2 PROTEINASE WITH ITS 11 AMINO ACID COFACTOR JRNL REF TO BE PUBLISHED JRNL REFN 0353 RESOLUTION 2.6 ANGSTROMS.
Sequence in PIR format:
>P1;1avpA structureX:1avpA: 1 :A: 204 :A:adenoviral proteinase:mastadenovirus h2: 9.99: 9.99 MGSSEQELKAIVKDLGCGPYFLGTYDKRFPGFVSPHKLACAIVNTAGRETGGVHWMAFAWNPRSKTCYLFEPFGF SDQRLKQVYQFEYESLLRRSAIASSPDRCITLEKSTQSVQGPNSAACGLFCCMFLHAFANWPQTPMDHNPTMNLI TGVPNSMLNSPQVQPTLRRNQEQLYSFLERHSPYFRSHSAQIRSATSFCHLKNM*
View SSTRUC file for 1avpA
Rasmol View of 1avpA