HEADER    HYDROLASE                               
COMPND    MOL_ID: 1;                                                  
COMPND   2 MOLECULE: METALLO-BETA-LACTAMASE;                          
COMPND   3 CHAIN: A, B;                                               
COMPND   4 SYNONYM: CLASS B BETA-LACTAMASE;                           
COMPND   5 EC: 3.5.2.6;                                               
COMPND   6 ENGINEERED: YES;                                           
COMPND   7 MUTATION: A171T, D208N                                     
SOURCE    MOL_ID: 1;                                                  
SOURCE   2 ORGANISM_SCIENTIFIC: BACTEROIDES FRAGILIS;                 
SOURCE   3 STRAIN: TAL3636;                                           
SOURCE   4 VARIANT: CLINICAL ISOLATE;                                 
SOURCE   5 GENE: CCRA;                                                
SOURCE   6 EXPRESSION_SYSTEM: ESCHERICHIA COLI                        
RESOLUTION  SOURCE               : NULL                       
AUTHOR    P.M.D.FITZGERALD,J.K.WU,J.H.TONEY                           
RESOLUTION     : KONNERT,HENDRICKSON                          
EXPDTA    X-RAY DIFFRACTION                                           
JRNL        AUTH   P.M.D.FITZGERALD,J.K.WU,J.H.TONEY                  
JRNL        TITL   UNANTICIPATED INHIBITION OF THE                    
JRNL        TITL 2 METALLO-BETA-LACTAMASE FROM BACTEROIDES FRAGILIS BY
JRNL        TITL 3 4-MORPHOLINEETHANESULFONIC ACID (MES): A           
JRNL        TITL 4 CRYSTALLOGRAPHIC STUDY AT 1.85-A RESOLUTION        
JRNL        REF    BIOCHEMISTRY                  V.  37  6791 1998    
JRNL        REFN   ASTM BICHAW  US ISSN 0006-2960                 0033
RESOLUTION   1.85 ANGSTROMS.                                  



 Sequence in PIR format: 
>P1;1a7tA
 structureX:1a7tA:   4 :A: 230 :A:metallo-beta-lactamase:bacteroides fragilis: 9.99: 9.99
 SVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTF
 IPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVW
 LPTENILFGGCMLKDNQTTSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGNYGGTELIEHTKQIVNQYIES
 TS*




 View SSTRUC file for 1a7tA 
 Rasmol View of  1a7tA