6PFK

phosphofructokinase, inhibited t-state

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 195
  • Norm. En. per Res.: -3.8968
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-66.9398	-133.1033	-552.828	-752.8711	195	17	21	23884	21	76	74
A-C	0.0	22.1751	-9.7339	12.4413	18	0	0	442	0	5	13
A-D	-77.8933	-16.4252	-370.334	-464.6525	143	21	9	14701	11	68	72
B-C	-79.2058	-17.1592	-358.379	-454.7439	136	11	9	14342	10	66	68
B-D	0.0	17.7373	-13.9909	3.7464	24	1	0	571	0	6	13
C-D	-59.4553	-157.9012	-542.513	-759.8695	195	21	19	23827	23	74	75

Interface residues

• A-B: ALA142A, ALA142B, ALA183A, ALA183B, ALA186A, ALA186B, ALA18A, ALA18B, ALA19A, ALA19B, ALA258A, ALA258B, ALA264A, ALA264B, ALA269A, ALA269B, ALA27A, ALA27B, ALA313A, ALA313B, ARG154A, ARG154B, ARG204B, ARG207A, ARG207B, ARG211A, ARG211B, ARG21A, ARG21B, ARG25A, ARG25B, ARG261A, ARG261B, ARG266A, ARG266B, ARG270A, ARG270B, ARG310A, ARG310B, ARG63A, ARG63B, ASN144A, ASN144B, ASN288A, ASN288B, ASN289A, ASN289B, ASP134A, ASP134B, ASP140A, ASP140B, ASP148A, ASP148B, ASP151A, ASP151B, ASP155A, ASP155B, ASP260A, ASP260B, ASP308A, ASP308B, ASP56A, ASP56B, ASP59A, ASP59B, GLN287A, GLN287B, GLN290A, GLN290B, GLU187A, GLU187B, GLU273A, GLU273B, GLU317A, GLU317B, GLU53A, GLU53B, GLY181A, GLY181B, GLY184A, GLY184B, GLY185A, GLY185B, GLY208B, GLY212A, GLY212B, GLY268A, GLY268B, GLY31A, GLY31B, GLY55A, GLY55B, GLY58A, GLY58B, HIS215A, HIS215B, HIS30A, HIS30B, HIS62A, HIS62B, ILE147A, ILE147B, ILE150A, ILE150B, ILE153A, ILE153B, ILE20A, ILE217A, ILE217B, ILE286A, ILE286B, ILE28A, ILE28B, ILE320A, ILE320B, ILE60A, ILE60B, ILE61A, ILE61B, LEU143A, LEU143B, LEU178A, LEU178B, LEU182A, LEU182B, LEU263A, LEU263B, LEU267A, LEU267B, LEU291A, LEU291B, LEU314A, LEU314B, LEU318A, LEU318B, LYS152A, LYS152B, LYS213A, LYS213B, LYS214A, LYS214B, LYS26A, LYS26B, LYS316A, LYS316B, MET311A, MET311B, PHE135A, PHE135B, PHE139A, PHE139B, PHE259A, PHE259B, PRO256A, PRO256B, SER180A, SER180B, SER22A, SER22B, SER255A, SER255B, SER265A, SER265B, SER315A, SER315B, SER319A, SER319B, THR133A, THR133B, THR141A, THR141B, THR145A, THR145B, THR156A, THR156B, THR257A, THR257B, TRP179A, TRP179B, TYR29A, TYR29B, VAL146A, VAL146B, VAL23A, VAL23B, VAL24A, VAL24B, VAL262A, VAL262B, VAL272A, VAL272B, VAL54A, VAL54B, VAL57A, VAL57B
• A-C: ARG63A, ARG63C, ASN17A, ASN17C, ASP59A, ASP59C, GLY254A, GLY254C, GLY64A, GLY64C, HIS62A, HIS62C, ILE60A, ILE60C, ILE67A, SER255A, SER255C, TYR69A
• A-D: ALA142A, ALA142D, ALA149A, ALA149D, ALA157A, ALA157D, ALA42A, ALA42D, ALA71A, ALA71D, ARG154A, ARG154D, ARG162D, ARG171D, ARG232D, ARG243A, ARG243D, ARG252A, ARG252D, ARG63A, ARG63D, ARG72A, ARG72D, ASN144A, ASN144D, ASN17A, ASN17D, ASP12A, ASP12D, ASP148A, ASP148D, ASP151A, ASP151D, ASP155A, ASP155D, ASP229A, CYS73A, CYS73D, GLN235D, GLN251A, GLN251D, GLU161A, GLU161D, GLU167A, GLU167D, GLU222D, GLU241A, GLU241D, GLY10A, GLY10D, GLY11A, GLY11D, GLY15A, GLY15D, GLY248A, GLY248D, GLY253A, GLY253D, GLY254A, GLY254D, GLY64A, GLY64D, GLY65A, GLY65D, HIS160A, HIS160D, HIS215A, HIS215D, HIS249A, HIS249D, HIS39A, HIS39D, HIS62A, HIS62D, ILE147D, ILE150A, ILE150D, ILE153A, ILE153D, ILE166A, ILE166D, ILE67A, ILE67D, LEU247A, LEU247D, LEU68A, LEU68D, LYS152A, LYS152D, LYS214A, LYS214D, MET169A, MET169D, MET16A, MET16D, PRO14A, PRO14D, PRO256A, PRO256D, SER13A, SER13D, SER159A, SER159D, SER226A, SER226D, SER255A, SER255D, SER9A, SER9D, THR141A, THR141D, THR145A, THR145D, THR156A, THR156D, THR158A, THR158D, THR163A, THR163D, THR245A, THR245D, THR66A, THR66D, THR70A, THR70D, THR8A, THR8D, TYR164A, TYR164D, TYR69A, TYR69D, VAL146A, VAL146D, VAL165A, VAL165D, VAL228A, VAL228D, VAL244A, VAL244D, VAL246A, VAL246D, VAL250A, VAL250D
• B-C: ALA142B, ALA142C, ALA149B, ALA149C, ALA157B, ALA157C, ALA42B, ALA71B, ALA71C, ARG154B, ARG154C, ARG162B, ARG162C, ARG243B, ARG243C, ARG252B, ARG252C, ARG63B, ARG63C, ARG72B, ARG72C, ASN144B, ASN144C, ASN17B, ASN17C, ASP12B, ASP12C, ASP148B, ASP148C, ASP151B, ASP151C, ASP155B, ASP155C, CYS73B, CYS73C, GLN235C, GLN251B, GLN251C, GLU161B, GLU161C, GLU167B, GLU167C, GLU222B, GLU241B, GLU241C, GLY10B, GLY10C, GLY11B, GLY11C, GLY15B, GLY248B, GLY248C, GLY253B, GLY253C, GLY254B, GLY254C, GLY64B, GLY64C, GLY65B, GLY65C, HIS160B, HIS160C, HIS215B, HIS215C, HIS249B, HIS249C, HIS39B, HIS39C, HIS62B, HIS62C, ILE147C, ILE150B, ILE150C, ILE153B, ILE153C, ILE166B, ILE166C, ILE67B, ILE67C, LEU247B, LEU247C, LEU68B, LEU68C, LYS152B, LYS152C, LYS214B, LYS214C, MET169B, MET169C, MET16B, MET16C, PRO14B, PRO14C, PRO256B, PRO256C, SER13B, SER13C, SER159B, SER159C, SER226B, SER226C, SER255B, SER255C, THR141B, THR141C, THR145B, THR145C, THR156B, THR156C, THR158B, THR158C, THR245B, THR245C, THR257C, THR66B, THR66C, THR70B, THR70C, THR8B, THR8C, TYR164B, TYR164C, TYR69B, TYR69C, VAL146B, VAL146C, VAL165B, VAL165C, VAL228B, VAL228C, VAL244B, VAL244C, VAL246B, VAL246C, VAL250B, VAL250C
• B-D: ARG63B, ARG63D, ASN17B, ASN17D, ASP59B, ASP59D, GLY254B, GLY254D, GLY64B, GLY64D, GLY65B, GLY65D, HIS62B, HIS62D, ILE60B, ILE60D, ILE67B, ILE67D, PRO256B, PRO256D, SER255B, SER255D, TYR69B, TYR69D
• C-D: ALA142C, ALA142D, ALA183C, ALA183D, ALA186C, ALA186D, ALA18C, ALA18D, ALA19C, ALA19D, ALA258C, ALA258D, ALA264C, ALA264D, ALA269C, ALA269D, ALA27C, ALA27D, ALA313C, ALA313D, ARG154C, ARG154D, ARG207C, ARG207D, ARG211C, ARG211D, ARG21C, ARG21D, ARG25C, ARG25D, ARG261C, ARG261D, ARG266C, ARG266D, ARG270C, ARG270D, ARG310C, ARG310D, ARG63C, ARG63D, ASN144C, ASN144D, ASN288C, ASN288D, ASN289C, ASN289D, ASP134C, ASP134D, ASP140C, ASP140D, ASP148C, ASP148D, ASP151C, ASP151D, ASP155C, ASP155D, ASP260C, ASP260D, ASP308C, ASP308D, ASP56C, ASP56D, ASP59C, ASP59D, GLN287C, GLN287D, GLN290C, GLN290D, GLU187C, GLU187D, GLU273C, GLU273D, GLU317C, GLU317D, GLU53C, GLU53D, GLY181C, GLY181D, GLY184C, GLY184D, GLY185C, GLY185D, GLY208D, GLY212C, GLY212D, GLY268C, GLY268D, GLY31C, GLY31D, GLY55C, GLY55D, GLY58C, GLY58D, HIS215C, HIS215D, HIS30C, HIS30D, HIS62C, HIS62D, ILE147C, ILE147D, ILE150C, ILE150D, ILE153C, ILE153D, ILE20C, ILE20D, ILE217C, ILE217D, ILE286C, ILE286D, ILE28C, ILE28D, ILE320C, ILE320D, ILE60C, ILE60D, ILE61C, ILE61D, LEU143C, LEU143D, LEU178C, LEU178D, LEU182C, LEU182D, LEU263C, LEU263D, LEU267C, LEU267D, LEU291C, LEU291D, LEU314C, LEU314D, LEU318C, LEU318D, LYS152C, LYS152D, LYS213C, LYS213D, LYS214C, LYS214D, LYS26C, LYS26D, LYS316C, LYS316D, MET311C, MET311D, PHE135C, PHE135D, PHE139C, PHE139D, PHE259C, PHE259D, PRO256C, PRO256D, SER180C, SER180D, SER22C, SER22D, SER255C, SER255D, SER265C, SER265D, SER315C, SER315D, SER319C, SER319D, THR133C, THR133D, THR141C, THR141D, THR145C, THR145D, THR156C, THR156D, THR257C, THR257D, TRP179C, TRP179D, TYR29C, TYR29D, VAL146C, VAL146D, VAL23C, VAL23D, VAL24C, VAL24D, VAL262C, VAL262D, VAL272C, VAL272D, VAL54C, VAL54D, VAL57C, VAL57D