4FAP

atomic structures of the rapamycin analogs in complex with both human fkbp12 and frb domain of frap

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 57
  • Norm. En. per Res.: -1.3493
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-6.6949	-0.4513	-69.7627	-76.9089	57	6	1	3265	0	12	20

Interface residues

• A-B: ALA81A, ALA84A, ARG131B, ARG198B, ARG42A, ASN132B, ASN182B, ASP191B, ASP37A, CYS22A, GLN188B, GLU107A, GLU121B, GLU130B, GLU54A, GLY129B, GLY181B, GLY83A, GLY86A, GLY89A, HIS195B, HIS87A, ILE56A, ILE90A, ILE91A, LEU186B, LEU192B, LYS184B, LYS34A, LYS35A, LYS44A, LYS47A, MET49A, PHE128B, PHE197B, PHE36A, PHE46A, PHE48A, PRO45A, PRO88A, PRO93A, SER124B, SER38A, THR187B, THR21A, THR85A, TRP190B, TYR127B, TYR177B, TYR194B, TYR26A, TYR82A, VAL133B, VAL183B, VAL23A, VAL24A, VAL55A