4AA6

the oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side- chain conformation

• Total interactions analyzed: 28
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 44
  • Norm. En. per Res.: -4.0221
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.5611	0.0	-136.412	-176.9731	44	8	1	4830	0	6	12
A-E	0.0	0.0	-4.5205	-4.5205	8	0	0	147	0	0	0
A-F	0.0	0.0	-0.0019	-0.0019	2	0	0	1	0	1	2
B-F	-12.6263	0.0	-25.7639	-38.3902	13	3	0	682	0	3	4
E-F	-10.9967	0.0	-90.6024	-101.5991	42	5	1	3483	0	0	1

Interface residues

• A-B: ALA223A, ALA223B, ALA239A, ALA239B, ARG233A, ARG233B, ARG234A, ARG234B, ASN225A, ASN225B, ASN232A, ASN232B, ASP218B, ASP230A, ASP230B, CYS221A, CYS221B, CYS227A, CYS227B, CYS237A, CYS237B, CYS240A, CYS240B, GLN226A, GLN226B, GLN238A, GLN238B, ILE229A, ILE229B, LYS231A, LYS235A, LYS235B, MET220A, MET220B, PRO222A, PRO222B, SER236A, SER236B, THR224A, THR224B, THR228A, THR228B, TYR219A, TYR219B
• A-E: ALA223E, ASN225E, ASP190A, CYS221E, MET220E, THR182A, TYR184A, TYR191A
• A-F: ASP230F, LYS231A
• B-F: ARG183F, ARG211B, ASN189F, ASP218B, GLN214B, GLY215B, HIS216B, ILE213B, SER212B, THR182F, TYR184F, TYR191F, TYR219B
• E-F: ALA223E, ALA223F, ALA239E, ALA239F, ARG233E, ARG234E, ARG234F, ASN225E, ASN225F, ASN232E, ASP218F, ASP230E, ASP230F, CYS221E, CYS221F, CYS227E, CYS227F, CYS237E, CYS237F, CYS240E, CYS240F, GLN226E, GLN226F, GLN238E, GLN238F, ILE229E, ILE229F, LYS231E, LYS235E, LYS235F, MET220E, MET220F, PRO222E, PRO222F, SER236E, SER236F, THR224E, THR224F, THR228E, THR228F, TYR219E, TYR219F