4A5O

crystal structure of pseudomonas aeruginosa n5, n10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold)

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 132
  • Norm. En. per Res.: -3.8715
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-61.1925	-64.9563	-389.0	-515.1488	135	18	12	16440	10	42	42
A-D	0.0	-19.4283	-42.8916	-62.3199	31	3	2	2042	1	8	9
C-D	-63.1415	-57.1114	-390.782	-511.0348	132	17	12	15817	6	43	42

Interface residues

• A-B: ALA107B, ALA132A, ALA132B, ALA162A, ALA162B, ALA167A, ALA167B, ALA176A, ALA176B, ALA203A, ALA203B, ARG113A, ARG113B, ARG130A, ARG130B, ARG134A, ARG134B, ARG173A, ARG173B, ARG191A, ARG191B, ARG194A, ARG194B, ARG202A, ARG202B, ASN127A, ASN127B, ASN169A, ASN169B, ASP106B, ASP156B, ASP161A, ASP161B, ASP195A, ASP195B, ASP198A, ASP198B, ASP204A, ASP204B, CYS184A, CYS184B, GLN133A, GLN133B, GLU112A, GLU112B, GLU178A, GLU178B, GLY122A, GLY129A, GLY129B, GLY159A, GLY159B, GLY172A, GLY172B, GLY182A, GLY182B, GLY183A, GLY183B, HIS124A, HIS124B, HIS190A, HIS190B, HIS199A, HIS199B, ILE128A, ILE128B, ILE170A, ILE170B, LEU109A, LEU109B, LEU111B, LEU131A, LEU131B, LEU137A, LEU137B, LEU157A, LEU157B, LEU177A, LEU177B, LEU179A, LEU179B, LEU180A, LEU180B, LEU181A, LEU181B, LEU196A, LEU196B, LEU205B, LYS222A, LYS222B, MET135A, MET135B, MET160A, MET160B, PHE123A, PHE123B, PHE192A, PHE192B, PRO116A, PRO116B, PRO125A, PRO125B, PRO136A, PRO136B, PRO140A, PRO140B, PRO143A, PRO174A, PRO174B, SER108A, SER108B, SER168A, SER168B, THR185A, THR185B, THR187A, THR187B, THR189A, THR189B, THR193A, THR193B, TYR126A, TYR126B, TYR158A, TYR158B, VAL163A, VAL163B, VAL164A, VAL164B, VAL171A, VAL171B, VAL186A, VAL186B, VAL188A, VAL188B
• A-D: ALA103A, ALA103D, ALA72A, ALA72D, ASP44A, ASP44D, ASP77D, ASP78D, GLN76A, GLN76D, GLU73A, GLU73D, GLY42A, GLY42D, HIS104A, HIS104D, LEU105A, LEU105D, PRO102A, PRO102D, PRO45A, PRO71A, PRO71D, SER75A, SER75D, THR43A, THR43D, THR74A, THR74D, VAL41A, VAL41D
• C-D: ALA107C, ALA132C, ALA132D, ALA162C, ALA162D, ALA167C, ALA167D, ALA176C, ALA176D, ALA203C, ALA203D, ARG113C, ARG113D, ARG130C, ARG130D, ARG134C, ARG134D, ARG173C, ARG173D, ARG191C, ARG191D, ARG194C, ARG194D, ARG202C, ARG202D, ASN127C, ASN127D, ASN169C, ASN169D, ASP106C, ASP156C, ASP156D, ASP161C, ASP161D, ASP195C, ASP195D, ASP198C, ASP198D, ASP204C, ASP204D, CYS184C, CYS184D, GLN133C, GLN133D, GLU112C, GLU112D, GLU178C, GLU178D, GLY129C, GLY129D, GLY159C, GLY159D, GLY166C, GLY172C, GLY172D, GLY182C, GLY182D, GLY183C, GLY183D, HIS124C, HIS124D, HIS190C, HIS190D, HIS199C, HIS199D, ILE128C, ILE128D, ILE170C, ILE170D, LEU109C, LEU109D, LEU111C, LEU111D, LEU131C, LEU131D, LEU137C, LEU137D, LEU157C, LEU157D, LEU177C, LEU177D, LEU179C, LEU179D, LEU180C, LEU180D, LEU181C, LEU181D, LEU196C, LEU196D, LYS222C, LYS222D, MET135C, MET135D, MET160C, MET160D, PHE123C, PHE123D, PHE192C, PHE192D, PRO116C, PRO116D, PRO125C, PRO125D, PRO136C, PRO174C, PRO174D, SER108C, SER108D, SER168C, SER168D, THR185C, THR185D, THR187C, THR187D, THR189C, THR189D, THR193C, THR193D, TYR126C, TYR126D, TYR158C, TYR158D, VAL163C, VAL163D, VAL164C, VAL164D, VAL165C, VAL171C, VAL186C, VAL186D, VAL188C, VAL188D