4A17

t.thermophila 60s ribosomal subunit in complex with initiation factor 6. this file contains 5s rrna, 5.8s rrna and proteins of molecule 2.

• Total interactions analyzed: 378
• Total true interactions: 34
• Strongest Interaction:
  • Chains: P-V
  • Int. Res.: 42
  • Norm. En. per Res.: -4.549
• Hub Node: C(8)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-F	-16.8863	0.0	-45.0521	-61.9384	31	1	2	2444	0	6	7
A-L	0.0	0.0	-2.3221	-2.3221	9	0	0	188	0	0	3
A-R	0.0	0.0	-0.2889	-0.2889	6	0	0	60	0	0	1
A-Y	-73.2144	-10.8213	-329.385	-413.4207	123	22	16	14371	1	21	23
B-I	-8.1809	-0.7886	-102.05	-111.0195	48	7	0	4268	1	5	23
B-J	-20.8485	31.282	-85.7514	-75.3179	52	8	2	3975	0	26	37
B-Q	0.0	0.0	-0.0027	-0.0027	2	0	0	4	0	0	1
B-T	0.0	-12.713	-96.5735	-109.2865	58	15	1	5110	0	13	18
C-H	-26.5333	-46.267	-62.8888	-135.6891	33	3	2	3156	1	19	7
C-K	0.0	0.0	-0.4794	-0.4794	3	0	0	85	0	0	0
C-L	0.0	37.5693	-52.4178	-14.8485	27	7	1	2213	0	2	26
C-N	-65.8024	-29.799	-244.131	-339.7324	97	54	13	12206	4	16	21
C-P	0.0	-75.4651	-56.3195	-131.7846	36	11	3	2628	4	10	7
C-Q	0.0	0.0	-0.0075	-0.0075	2	0	0	6	0	0	3
C-S	-3.2937	39.2422	-14.4048	21.5437	21	9	0	1233	0	0	19
C-V	-30.426	19.4518	-211.4	-222.3743	112	21	5	10551	0	19	38
D-M	-11.1888	20.536	-42.4751	-33.1279	35	4	1	2311	0	8	16
E-I	0.0	-6.2999	-13.6881	-19.988	17	5	0	791	0	2	10
F-L	-19.3471	-18.0244	-201.099	-238.4704	90	10	4	9820	4	25	22
F-R	-14.6752	20.868	-88.4179	-82.225	26	4	6	3732	0	2	9
H-M	0.0	0.0	-18.533	-18.533	21	2	2	1361	0	6	6
H-P	-16.7361	0.0	-21.9485	-38.6846	22	3	1	1318	0	3	2
J-T	-37.8667	-16.084	-143.555	-197.5057	52	8	4	5856	2	13	18
K-L	0.0	3.253	-0.3032	2.9498	4	0	0	56	0	0	4
K-N	-18.1012	-5.5689	-194.493	-218.1632	82	24	3	8414	3	23	37
K-X	0.0	18.8119	-14.7771	4.0348	17	4	0	934	0	1	15
L-U	-11.4268	-6.597	-67.4435	-85.4673	39	6	0	3214	0	14	20
M-P	-69.603	-17.0233	-213.128	-299.7543	75	43	5	9401	2	14	45
N-P	0.0	0.0	-0.0007	-0.0007	2	0	0	2	0	1	3
N-V	-10.5288	-44.6256	-54.0575	-109.212	31	10	1	2597	2	11	10
O-R	0.0	0.0	-0.0537	-0.0537	3	0	0	25	0	2	2
P-V	-64.1389	4.8601	-131.779	-191.0578	42	9	6	4846	1	2	6
Q-W	0.0	6.9096	-0.0286	6.881	3	0	0	7	0	4	4
R-U	-13.2705	-4.5849	-151.393	-169.2485	73	19	6	7733	0	11	30

Interface residues

• A-F: ALA36A, ARG30F, ARG38A, ARG39F, ARG43A, ARG65A, ARG69A, ASP34A, ASP34F, ASP66A, GLN36F, GLN39A, GLU37A, GLY32F, GLY33F, GLY40A, ILE35F, ILE42A, LEU41F, LEU93A, LYS38F, LYS71A, LYS94A, PHE29F, PHE35A, PRO37F, PRO67A, TYR41A, TYR68A, TYR70A, VAL31F
• A-L: ALA232A, ARG12A, ARG3A, ARG9A, GLN8A, GLY2A, ILE5A, LYS77L, VAL4A
• A-R: ARG36R, ARG69A, GLY34R, THR33R, TYR68A, VAL35R
• A-Y: ALA171A, ALA183A, ALA50Y, ALA51Y, ALA57A, ALA60A, ALA65Y, ALA68Y, ALA76Y, ALA79A, ALA79Y, ALA80A, ALA98A, ARG107A, ARG175A, ARG17Y, ARG23Y, ARG47A, ARG49Y, ARG55A, ARG85Y, ASN101A, ASN106A, ASN185A, ASN84Y, ASP177A, ASP48A, GLN33Y, GLN83A, GLN87A, GLN90Y, GLN96A, GLU110A, GLU30Y, GLU52A, GLU70Y, GLU81A, GLU91Y, GLY100A, GLY111A, GLY132A, GLY168A, GLY172A, GLY173A, GLY174A, GLY184A, GLY19Y, GLY53Y, GLY56A, GLY66Y, GLY67Y, GLY82A, GLY86A, HIS140A, HIS34Y, HIS51A, ILE108A, ILE10Y, ILE137A, ILE169A, ILE180A, ILE31Y, ILE46A, ILE49A, ILE54Y, ILE63Y, ILE64Y, ILE78A, ILE97A, LEU181A, LEU22Y, LEU59A, LEU71Y, LEU86Y, LEU89Y, LYS13Y, LYS178A, LYS182A, LYS24Y, LYS27Y, LYS28Y, LYS56Y, LYS61Y, LYS62Y, LYS80Y, LYS87Y, LYS88Y, MET83Y, PHE29Y, PHE41Y, PRO109A, PRO179A, PRO40Y, PRO58A, PRO74Y, PRO75Y, SER131A, SER21Y, SER85A, THR112A, THR11Y, THR176A, THR32Y, THR72Y, THR73Y, THR78Y, THR82Y, TRP55Y, TRP69Y, TYR134A, TYR14Y, TYR18Y, TYR84A, VAL113A, VAL114A, VAL167A, VAL170A, VAL25Y, VAL26Y, VAL50A, VAL52Y, VAL77Y, VAL99A
• B-I: ALA74I, ARG17B, ARG19B, ARG20B, ARG257B, ARG259B, ARG66I, ARG67I, ARG97B, ASN62I, ASN64I, ASP94B, GLN149I, GLU105I, GLY106I, GLY147I, GLY98B, HIS254B, HIS63I, ILE107I, ILE152I, ILE258B, ILE93B, LEU14B, LEU151I, LEU155I, LEU99B, LYS148I, LYS154I, LYS158I, MET61I, PHE104I, PHE260B, PRO108I, PRO18B, PRO255B, PRO65I, PRO96B, SER154B, SER256B, THR109I, THR150I, THR261B, THR95B, TRP146I, TRP60I, TYR152B, VAL262B
• B-J: ALA15J, ALA75B, ALA8B, ARG10B, ARG4B, ARG58B, ARG66B, ARG90J, ARG91J, ARG92J, ASN68B, ASP128J, ASP93J, CYS126J, GLN10J, GLU125J, GLU71B, GLU74B, GLU7B, GLY12J, GLY232B, GLY48J, GLY59J, GLY94J, HIS11B, HIS49J, HIS55B, HIS67B, ILE129J, ILE56B, LEU50J, LEU53J, LEU57B, LYS124J, LYS14J, LYS16J, LYS234B, LYS52J, LYS5B, LYS69B, LYS70B, PHE6B, PRO9B, SER51J, SER65B, THR13J, VAL17J, VAL233B, VAL60B, VAL72B, VAL73B, VAL95J
• B-Q: ARG21B, ARG71Q
• B-T: ALA295B, ARG14T, ARG19T, ARG367B, ARG4T, ARG58T, ASP297B, ASP358B, CYS11T, CYS8T, GLN369B, GLU12T, GLU373B, GLU71B, GLU74B, GLY18T, GLY20T, GLY296B, GLY364B, GLY366B, HIS365B, HIS55B, ILE15T, ILE357B, ILE363B, ILE55T, ILE56B, LEU34T, LEU57B, LYS301B, LYS355B, LYS362B, LYS36T, LYS376B, LYS37T, PHE356B, PHE368B, PHE377B, PHE378B, PRO17T, SER293B, SER360B, SER361B, THR294B, THR299B, THR359B, THR35T, THR370B, THR54T, THR5T, TRP53T, TYR13T, TYR16T, VAL298B, VAL2T, VAL3T, VAL72B, VAL73B
• C-H: ALA179H, ALA400C, ARG178H, ARG183H, ARG185H, ASN186H, ASP397C, ASP409C, GLN169H, GLN180H, GLN187H, GLN401C, GLN403C, GLU142H, GLU404C, GLU407C, GLU410C, GLU44H, GLY402C, GLY408C, ILE399C, ILE405C, LEU184H, LYS141H, LYS170H, LYS406C, PHE398C, PRO47H, SER182H, THR177H, TRP171H, TYR181H, TYR48H
• C-K: ARG118C, LYS47C, VAL2K
• C-L: ALA52C, ARG114C, ARG115C, ARG118C, ARG119C, ARG201L, ARG202L, ARG204L, ARG49C, ASN121C, ASN48C, ASP44C, GLN51C, HIS117C, LEU198L, LEU200L, LEU45C, LYS111C, LYS125C, LYS199L, LYS47C, LYS50C, THR112C, TYR113C, TYR203L, VAL116C, VAL120C
• C-N: ALA103N, ALA128N, ALA131C, ALA131N, ALA134C, ALA291C, ALA293C, ALA296C, ALA311C, ALA31C, ARG111N, ARG287C, ARG297C, ARG34C, ARG39N, ARG40N, ARG57N, ASN123C, ASN24N, ASN292C, ASN300C, ASN302C, ASN46N, ASP125N, ASP294C, ASP36C, ASP42N, GLN124C, GLN126N, GLN284C, GLN286C, GLN305C, GLN47N, GLU108N, GLU303C, GLY134N, GLY282C, GLY312C, HIS127C, HIS27N, HIS39C, ILE295C, ILE298C, ILE299C, ILE31N, ILE33C, ILE37C, LEU104N, LEU115N, LEU122N, LEU127N, LEU129N, LEU138C, LEU285C, LEU289C, LEU290C, LEU29N, LEU30N, LEU33N, LEU37N, LEU53N, LYS105N, LYS112N, LYS130N, LYS28N, LYS309C, LYS32N, LYS35N, PHE106N, PHE124N, PHE36N, PRO132N, PRO288C, PRO32C, SER22N, SER301C, SER306C, SER43N, THR107N, THR123N, THR133N, THR135N, THR23N, THR276C, THR30C, THR35C, THR41N, TYR26N, TYR273C, TYR34N, VAL252C, VAL25N, VAL304C, VAL307C, VAL308C, VAL310C, VAL38N
• C-P: ALA379C, ALA383C, ALA387C, ALA391C, ALA396C, ALA400C, ARG154P, ARG392C, ASN146P, ASN381C, ASN384C, ASP395C, ASP397C, GLN148P, GLN393C, GLN401C, GLU155P, GLU385C, GLU386C, GLU394C, HIS149P, ILE156P, ILE388C, ILE399C, LYS151P, LYS382C, LYS390C, PHE147P, PHE153P, PHE157P, PHE380C, PHE398C, PRO150P, TRP376C, VAL145P, VAL152P
• C-Q: ARG130Q, HIS90C
• C-S: ALA10S, ARG11S, ARG12S, ARG15S, ARG202C, ARG204C, ARG205C, ARG228C, ASN203C, ASN229C, GLN14S, GLY199C, HIS4S, LEU194C, LEU201C, LYS13S, LYS200C, LYS2S, SER8S, SER9S, THR3S
• C-V: ALA151V, ALA311C, ALA329C, ALA336C, ALA337C, ALA365C, ALA366C, ALA375C, ALA379C, ALA39V, ALA45V, ALA49V, ALA66V, ALA71V, ARG148V, ARG157V, ARG15V, ARG297C, ARG319C, ARG37V, ARG64V, ARG67V, ASN139V, ASN154V, ASN163V, ASN300C, ASN302C, ASN322C, ASN326C, ASN334C, ASN8V, ASP162V, ASP180V, CYS177V, GLN156V, GLN305C, GLN343C, GLN46V, GLU179V, GLU303C, GLU315C, GLU318C, GLU40V, GLU53V, GLU7V, GLY149V, GLY372C, GLY70V, HIS317C, HIS369C, ILE145V, ILE158V, ILE165V, ILE182V, ILE339C, ILE42V, LEU144V, LEU160V, LEU19V, LEU239V, LEU324C, LEU330C, LEU333C, LYS11V, LYS12V, LYS143V, LYS147V, LYS168V, LYS18V, LYS309C, LYS320C, LYS321C, LYS332C, LYS338C, LYS370C, LYS371C, LYS38V, LYS44V, LYS47V, LYS68V, MET34V, PHE150V, PHE202V, PHE331C, PHE72V, PRO159V, PRO323C, PRO335C, SER142V, SER301C, SER306C, SER373C, SER43V, THR140V, THR161V, THR164V, THR176V, THR316C, THR325C, THR368C, THR69V, TRP376C, TRP41V, TYR146V, TYR48V, TYR52V, VAL153V, VAL166V, VAL178V, VAL308C, VAL310C, VAL340C
• D-M: ALA144D, ALA148M, ALA32M, ALA53M, ALA55M, ARG137D, ARG141D, ARG142D, ARG143D, ARG147D, ARG152M, ARG22M, ARG23M, ARG24M, ARG54M, ASN57M, ASN98D, ASP29M, GLU25M, GLY149M, GLY26M, ILE61M, LEU150M, LEU27M, LYS19M, LYS8M, PHE16M, SER146D, THR145D, THR153M, THR28M, THR56M, TYR12M, VAL151M, VAL4M
• E-I: ALA41E, ALA60E, ARG129I, ARG132I, ARG23E, ARG2E, ASN130I, GLN59E, GLU64E, ILE57E, LYS63E, SER131I, SER42E, SER61E, TYR40E, VAL43E, VAL67E
• F-L: ALA3L, ARG222F, ARG24L, ARG26L, ARG31L, ARG41L, ARG44L, ARG49F, ARG49L, ARG55F, ARG58F, ARG63L, ARG65L, ASN130F, ASN166F, ASP151F, ASP17L, ASP46L, GLN161F, GLN32L, GLN54F, GLN56F, GLN62F, GLN69F, GLU137F, GLU154F, GLU29L, GLU9L, GLY128F, GLY226F, GLY227F, GLY2L, HIS131F, HIS37L, HIS71F, ILE132F, ILE136F, ILE153F, ILE157F, ILE22L, ILE70F, LEU10L, LEU129F, LEU155F, LEU159F, LEU162F, LEU18L, LEU23L, LEU25L, LEU33L, LEU53F, LEU60F, LEU61F, LEU64F, LEU7L, LYS165F, LYS176F, LYS186F, LYS57F, LYS5L, LYS65F, MET19L, PHE158F, PHE21L, PRO152F, PRO34L, PRO45L, PRO67F, PRO68F, SER16L, SER20L, SER42L, SER43L, THR133F, THR134F, THR187F, THR189F, THR52F, TRP11L, TRP225F, TRP28L, TYR30L, TYR4L, TYR50F, TYR6L, VAL150F, VAL156F, VAL35L, VAL59F, VAL66F
• F-R: ARG36R, ARG39F, ARG39R, ARG43F, ARG46F, ARG55F, ASP40F, GLY34R, ILE51F, LEU41F, LYS30R, LYS38F, PHE37R, PHE38R, PHE44F, PRO37F, PRO40R, PRO48F, THR31R, THR33R, THR42F, TRP47F, TYR32R, TYR50F, VAL35R, VAL45F
• H-M: ALA298M, ARG203H, ARG213H, ARG287M, ARG290M, GLN296M, GLN301M, GLU202H, GLY204H, LEU206H, LEU209H, LEU211H, LEU297M, LEU299M, LYS288M, LYS292M, LYS294M, PHE212H, PHE295M, THR293M, VAL291M
• H-P: ARG12P, ARG154P, ARG90H, GLN169H, GLU155P, GLY132H, HIS51H, ILE134H, ILE156P, LYS164H, LYS170H, LYS175H, PHE157P, SER133H, SER168H, THR167H, THR177H, TYR22H, VAL165H, VAL166H, VAL49H, VAL53H
• J-T: ALA123J, ALA25T, ARG19T, ARG22T, ARG29T, ARG4T, ARG84J, ARG86J, ARG90J, ARG91J, ASN28J, ASP101J, ASP27T, ASP93J, CYS40T, GLN21T, GLN85J, GLU100J, GLY120J, GLY18T, GLY20T, GLY28T, GLY30T, GLY6T, GLY94J, ILE15T, ILE24T, ILE58J, ILE97J, LEU43T, LYS124J, LYS26T, LYS36T, LYS39T, PHE23T, PHE31T, PHE32T, PHE33T, PHE96J, PHE99J, PRO121J, PRO17T, PRO88J, SER139J, THR119J, TRP89J, TYR16T, TYR98J, VAL122J, VAL140J, VAL141J, VAL95J
• K-L: HIS179L, HIS64K, LYS182L, LYS66K
• K-N: ALA155N, ALA164N, ALA177N, ARG113N, ARG117K, ARG168N, ARG172N, ARG176N, ARG44K, ARG61K, ARG89K, ARG92N, ASN120K, ASN76K, ASN89N, ASP78K, ASP86K, ASP90N, GLN121K, GLN158N, GLN90K, GLU170N, GLU175N, GLU48K, GLU91N, GLY116K, GLY157N, GLY171N, GLY179N, GLY39K, GLY53K, GLY56K, GLY59K, HIS151N, HIS178N, HIS41K, HIS43K, HIS51K, ILE45K, ILE77K, LEU118K, LEU180N, LEU46K, LEU58K, LEU65K, LEU80K, LEU83K, LEU93N, LEU94N, LYS112N, LYS115K, LYS154N, LYS173N, LYS181N, LYS36K, LYS49K, LYS57K, LYS67K, LYS79K, MET40K, MET47K, MET60K, PHE174N, PHE63K, PRO119K, PRO156N, PRO165N, PRO52K, SER161N, SER163N, SER169N, SER82K, SER85K, THR62K, THR95N, TRP50K, TRP81K, TYR166N, TYR54K, TYR55K, VAL167N, VAL96N
• K-X: ARG12K, ARG21K, ARG35X, ARG36X, ARG38X, ARG45X, ASN42X, ASP41X, GLY13K, GLY39X, HIS14K, ILE40X, LEU11K, LYS10K, PRO37X, SER16K, VAL15K
• L-U: ALA103U, ALA141L, ALA91U, ARG101U, ARG114L, ARG143L, ARG147L, ARG90U, ARG93U, ARG94U, ASN140L, ASN144L, ASN149L, ASP145L, CYS152L, GLN100U, GLU102U, GLU153L, HIS139L, HIS156L, ILE142L, ILE148L, ILE151L, ILE92U, LEU105U, LEU96U, LYS107U, LYS157L, LYS95U, LYS99U, PRO137L, PRO146L, SER138L, SER154L, THR108U, THR97U, TRP150L, VAL104U, VAL106U
• M-P: ALA11M, ALA18P, ALA67M, ARG15M, ARG22M, ARG26P, ARG29P, ARG33M, ARG35M, ARG50M, ARG70P, ASN45M, ASN66P, ASN68P, ASP29M, ASP40M, ASP42M, ASP72M, CYS71M, GLN17M, GLN39M, GLN48P, GLU38P, GLU94P, GLY23P, GLY37P, HIS24P, ILE27P, ILE37M, ILE38M, ILE72P, ILE93P, LEU31P, LEU69M, LYS14M, LYS17P, LYS19M, LYS20P, LYS22P, LYS34M, LYS35P, LYS41M, LYS43M, LYS48M, LYS70M, LYS92P, PHE13M, PHE16M, PRO47M, PRO69P, PRO98P, SER28P, SER47P, SER71P, THR18M, THR21P, THR28M, THR32P, THR33P, THR46M, THR68M, TYR12M, TYR19P, TYR20M, TYR30M, TYR30P, TYR31M, TYR34P, TYR44M, TYR66M, VAL25P, VAL36P, VAL64P, VAL67P, VAL96P
• N-P: ARG83P, LYS154N
• N-V: ALA2N, ARG101V, ARG104V, ARG106V, ARG15V, ARG40N, ARG85V, ARG98V, ASN110V, ASN90V, ASP4N, GLN107V, GLN8N, GLY88V, GLY9N, HIS6N, ILE3N, LEU100V, LEU105V, LEU108V, LEU19V, LEU5N, LEU92V, LYS203V, LYS7N, LYS97V, PHE36N, PRO201V, TRP200V, VAL89V, VAL96V
• O-R: ARG38O, LYS82R, SER37O
• P-V: ALA119V, ALA138P, ALA66V, ALA71V, ALA76V, ALA78V, ARG115V, ASN117V, ASN131P, GLN134P, GLN140P, GLN142P, GLU137P, GLU62V, GLU77V, GLY133P, GLY143P, GLY70V, ILE59V, LEU121V, LEU136P, LYS118V, LYS129P, LYS193V, LYS58V, LYS65V, LYS79V, PHE72V, PRO132P, PRO135P, PRO75V, SER120V, THR69V, TYR135V, TYR73V, VAL116V, VAL139P, VAL141P, VAL145P, VAL188V, VAL74V, VAL80V
• Q-W: ASP46W, ASP55Q, LYS57Q
• R-U: ALA144R, ALA35U, ALA38U, ALA57R, ALA69U, ARG33U, ARG53R, ARG56R, ARG66U, ARG67U, ARG85U, ASN63U, ASP66R, ASP83U, GLN26U, GLN31U, GLN68U, GLN73U, GLU15U, GLY148R, GLY23U, GLY39U, HIS58R, HIS68R, ILE147R, ILE150R, ILE34U, ILE37U, ILE55U, ILE62U, ILE84U, LEU110R, LEU143R, LEU149R, LEU22U, LEU29U, LEU59R, LEU59U, LEU75R, LEU79U, LEU82U, LYS146R, LYS36U, LYS44U, LYS50R, LYS60R, LYS65U, LYS71U, LYS72R, LYS77U, LYS80U, PHE74U, PHE92R, PRO74R, PRO81U, SER30U, SER52R, SER62R, SER69R, SER78U, THR27U, THR54R, THR73R, THR76R, THR77R, TYR111R, TYR51R, TYR93R, VAL55R, VAL61R, VAL70U, VAL71R, VAL91R