4A0K

structure of ddb1-ddb2-cul4a-rbx1 bound to a 12 bp abasic site containing dna-duplex

• Total interactions analyzed: 15
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 116
  • Norm. En. per Res.: -5.9711
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-181.4846	-21.5054	-489.652	-692.642	116	40	19	19083	2	29	27
A-C	-8.5492	-54.2082	-279.92	-342.6774	140	29	5	13273	3	51	36
C-D	-24.0766	-12.5048	-249.516	-286.0974	185	23	8	13598	2	49	49

Interface residues

• A-B: ALA29B, ALA31B, ALA34B, ALA458A, ALA576A, ALA580A, ARG21B, ARG565A, ARG666A, ASN28B, ASN526A, ASN603A, ASN657A, ASN670A, ASP36B, ASP497A, ASP522A, ASP606A, GLN551A, GLN568A, GLN570A, GLN590A, GLU23B, GLU546A, GLU552A, GLU581A, GLU588A, GLU604A, GLY464A, GLY519A, GLY531A, GLY564A, GLY574A, GLY605A, GLY607A, GLY658A, HIS562A, HIS575A, ILE37B, ILE521A, ILE527A, ILE548A, ILE655A, ILE669A, LEU32B, LEU462A, LEU500A, LEU523A, LEU528A, LEU543A, LEU550A, LEU559A, LEU567A, LEU573A, LEU578A, LEU593A, LEU597A, LEU599A, LEU600A, LEU631A, LEU639A, LYS19B, LYS20B, LYS25B, LYS26B, LYS509A, LYS549A, LYS555A, LYS566A, LYS579A, LYS583A, LYS587A, MET498A, MET505A, MET530A, MET547A, MET601A, PHE22B, PHE554A, PHE582A, PHE589A, PHE602A, PHE656A, PHE660A, PRO520A, PRO534A, PRO538A, SER501A, SER563A, SER592A, THR524A, THR529A, THR535A, THR537A, THR544A, THR571A, THR572A, THR596A, TRP27B, TRP33B, TRP35B, TRP533A, TRP569A, TYR532A, TYR536A, TYR558A, VAL24B, VAL30B, VAL38B, VAL39B, VAL463A, VAL525A, VAL577A, VAL591A, VAL598A, VAL638A
• A-C: ALA400C, ALA501C, ALA511C, ALA539C, ALA610C, ALA89A, ARG144A, ARG150A, ARG158A, ARG434C, ARG49A, ARG514C, ARG51A, ARG53A, ARG589C, ARG80A, ASN439C, ASN47A, ASN497C, ASN677C, ASN696C, ASN82A, ASN92A, ASP157A, ASP403C, ASP453C, ASP454C, ASP50A, ASP608C, ASP654C, CB7.527220.80005, CYS143A, CYS540C, CYS94A, GLN163A, GLN432C, GLN455C, GLN456C, GLN634C, GLN731C, GLN88A, GLU398C, GLU441C, GLU442C, GLU444C, GLU445C, GLU447C, GLU537C, GLU585C, GLU675C, GLU84A, GLU85A, GLU91A, GLY406C, GLY431C, GLY513C, GLY559C, GLY584C, GLY607C, GLY609C, GLY632C, HIS399C, HIS536C, HIS96A, ILE147A, ILE149A, ILE152A, ILE402C, ILE407C, ILE45A, ILE498C, ILE564C, ILE586C, ILE587C, ILE701C, ILE79A, LEU154A, LEU162A, LEU404C, LEU427C, LEU436C, LEU43A, LEU606C, LEU699C, LEU83A, LEU86A, LEU93A, LYS408C, LYS41A, LYS41A5, LYS42A, LYS46A, LYS496C, MET146A, MET148A, MET437C, PHE153A, PHE155A, PHE429C, PHE458C, PHE48A, PRO405C, PRO52A, PRO588C, PRO635C, SER151A, SER165A, SER401C, SER428C, SER473C, SER499C, SER697C, SER95A, THR159A, THR433C, THR446C, THR562C, THR59A, THR630C, THR633C, THR636C, THR698C, THR700C, TRP171A, TRP561C, TYR160A, TYR58A, TYR678C, TYR687C, TYR81A, TYR87A, VAL430C, VAL435C, VAL443C, VAL44A, VAL500C, VAL512C, VAL538C, VAL637C, VAL90A
• C-D: ALA120D, ALA381C, ALA813C, ALA834C, ALA841C, ALA869C, ARG1080C, ARG114C, ARG123D, ARG132D, ARG158C, ARG188C, ARG249D, ARG289D, ARG309D, ARG327C, ARG454D, ARG722C, ARG928C, ARG947C, ASN1005C, ASN1034C, ASN287D, ASN810C, ASN885C, ASN907C, ASN908C, ASN970C, ASP184C, ASP291D, ASP336D, ASP361C, ASP439D, ASP925C, CYS125D, CYS290D, CYS378C, GLN102D, GLN116D, GLN121D, GLN124D, GLN127D, GLN183C, GLN186C, GLN202D, GLN234C, GLN250D, GLN845C, GLU1079C, GLU117C, GLU128D, GLU160C, GLU161C, GLU215C, GLU312C, GLU455D, GLU719C, GLU784C, GLU785C, GLU787C, GLU839C, GLU840C, GLU842C, GLU987C, GLY101D, GLY113C, GLY115D, GLY119C, GLY138C, GLY187C, GLY357C, GLY380C, GLY385C, GLY438D, GLY868C, HIS107D, HIS119D, HIS156D, HIS159D, HIS163C, HIS789C, HIS991C, ILE105D, ILE109D, ILE112C, ILE118D, ILE131D, ILE165C, ILE310C, ILE359C, ILE740C, ILE909C, LEU106D, LEU114D, LEU126D, LEU134D, LEU139C, LEU159C, LEU162C, LEU293D, LEU328C, LEU814C, LEU912C, LEU926C, LYS111D, LYS135D, LYS723C, LYS844C, MET276C, MET384D, MET835C, MET910C, MET927C, MET954C, PHE1003C, PHE130D, PHE203D, PHE332D, PHE382C, PHE949C, PHE972C, PRO115C, PRO129D, PRO157D, PRO160D, PRO185C, PRO288D, PRO334D, PRO358C, PRO383D, PRO436D, PRO721C, PRO838C, PRO843C, PRO951C, SER104D, SER112D, SER113D, SER116C, SER117D, SER133D, SER136D, SER246D, SER248D, SER337D, SER354D, SER379C, SER435D, SER720C, SER737C, SER738C, SER886C, SER955C, THR1032C, THR103D, THR118C, THR158D, THR205D, THR257C, THR335D, THR338D, THR437D, THR833C, TRP292D, TRP357D, TRP953C, TYR108D, TYR110D, TYR137D, TYR182C, TYR385D, TYR812C, TYR837C, TYR871C, TYR906C, TYR913C, VAL1004C, VAL1033C, VAL247D, VAL259C, VAL360C, VAL440D, VAL786C, VAL836C, VAL870C