3ZQ4

unusual, dual endo- and exo-nuclease activity in the degradosome explained by crystal structure analysis of rnase j1

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: D-E
  • Int. Res.: 246
  • Norm. En. per Res.: -3.8084
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-74.3997	-152.1546	-647.923	-874.4773	248	42	20	27530	11	88	84
A-D	0.0	-3.1137	-11.1003	-14.214	8	2	0	565	2	12	13
A-E	-21.2344	-23.0197	-221.831	-266.0851	99	7	8	10072	4	49	50
C-D	-20.9085	-37.4701	-206.975	-265.3536	99	7	8	9681	4	49	51
C-E	0.0	-8.202	-9.7388	-17.9408	8	3	0	528	1	11	11
D-E	-84.3202	-194.7639	-657.787	-936.8711	246	56	16	27550	13	88	88

Interface residues

• A-C: ALA351A, ALA351C, ALA353A, ALA353C, ALA482A, ALA482C, ARG343A, ARG343C, ARG350A, ARG350C, ARG394A, ARG394C, ARG456A, ARG456C, ARG458A, ARG458C, ARG459A, ARG459C, ARG489A, ARG489C, ARG495A, ARG544A, ARG544C, ARG545A, ARG545C, ASN201A, ASN201C, ASN337A, ASN337C, ASN346A, ASN346C, ASN418A, ASN418C, ASN452C, ASP417A, ASP417C, ASP443A, ASP443C, ASP449A, ASP449C, ASP457A, ASP457C, ASP45A, ASP45C, ASP474A, ASP474C, ASP485A, ASP485C, ASP51A, ASP51C, GLN347A, GLN347C, GLN371A, GLN371C, GLN396A, GLN396C, GLU19A, GLU19C, GLU200A, GLU200C, GLU354A, GLU354C, GLU392A, GLU392C, GLU420A, GLU420C, GLU44A, GLU44C, GLU463A, GLU463C, GLU464A, GLU464C, GLU46A, GLU46C, GLU496A, GLU540A, GLU540C, GLU554A, GLU554C, GLY18A, GLY18C, GLY336A, GLY336C, GLY352A, GLY352C, GLY391A, GLY391C, GLY444A, GLY444C, GLY446A, GLY446C, GLY448A, GLY448C, GLY451A, GLY451C, GLY465A, GLY465C, GLY483A, GLY483C, GLY490A, GLY490C, GLY49A, GLY49C, HIS357A, HIS357C, ILE334A, ILE334C, ILE339A, ILE339C, ILE345A, ILE345C, ILE415A, ILE415C, ILE442A, ILE442C, ILE447A, ILE447C, ILE450A, ILE450C, ILE453A, ILE453C, ILE460A, ILE460C, ILE468A, ILE468C, ILE473A, ILE473C, ILE480A, ILE480C, ILE487A, ILE487C, ILE50A, ILE50C, ILE548C, ILE551A, ILE551C, ILE552A, ILE552C, LEU17A, LEU17C, LEU348A, LEU348C, LEU360A, LEU360C, LEU455A, LEU455C, LEU461A, LEU461C, LEU466A, LEU466C, LEU47A, LEU47C, LEU486A, LEU486C, LEU48A, LEU48C, LEU500A, LEU538A, LEU538C, LEU549A, LEU549C, LYS397A, LYS397C, LYS41A, LYS41C, LYS527A, LYS527C, LYS541A, LYS541C, LYS543A, LYS543C, MET395A, MET395C, MET398A, MET398C, MET416A, MET416C, MET475A, MET494A, MET547A, MET547C, MET553A, MET553C, PHE491A, PHE491C, PRO202A, PRO202C, PRO304A, PRO304C, PRO333A, PRO333C, PRO335A, PRO335C, PRO484A, PRO484C, PRO546A, PRO546C, PRO550A, PRO550C, SER340A, SER340C, SER342A, SER342C, SER445A, SER445C, SER462A, SER462C, SER472A, SER472C, SER481A, SER481C, SER488A, SER488C, SER497A, THR338A, THR338C, THR344A, THR344C, THR542A, THR542C, TRP523A, TRP523C, TYR349A, TYR349C, TYR393A, TYR393C, TYR441A, TYR493A, TYR539A, TYR539C, VAL341A, VAL341C, VAL355A, VAL355C, VAL454A, VAL454C, VAL467A, VAL467C, VAL469A, VAL469C, VAL470A, VAL470C, VAL471A, VAL471C, VAL492A, VAL492C, VAL555A, VAL555C
• A-D: ARG220A, ARG220D, ASP217A, ASP217D, ILE218A, ILE218D, LYS221A, LYS221D
• A-E: ALA176A, ALA176E, ALA182A, ALA182E, ALA403A, ALA403E, ARG209A, ARG209E, ARG210A, ARG210E, ARG379A, ARG379E, ASN177A, ASN177E, ASP168A, ASP168E, ASP405A, ASP405E, CYS406A, CYS406E, GLN371A, GLN371E, GLN374A, GLN374E, GLU174A, GLU174E, GLU183A, GLU183E, GLU187A, GLU187E, GLU203A, GLU203E, GLU213A, GLU213E, GLU372A, GLU372E, GLU373A, GLU373E, GLY173A, GLY173E, GLY185A, GLY185E, GLY188A, GLY407A, GLY407E, ILE184A, ILE184E, ILE381A, ILE381E, LEU178A, LEU178E, LEU376A, LEU376E, LEU378A, LEU378E, LEU380A, LEU380E, LEU402A, LEU402E, LYS180A, LYS180E, LYS186A, LYS186E, LYS375A, LYS375E, LYS382A, LYS382E, LYS401A, LYS401E, MET181A, MET181E, MET206A, MET206E, MET377A, MET377E, MET398A, MET398E, PHE167A, PHE167E, PHE169A, PHE169E, PHE204A, PHE204E, PRO171A, PRO171E, PRO175A, PRO175E, PRO202A, PRO202E, SER207A, SER207E, THR170A, THR170E, THR179A, THR179E, THR205A, THR205E, THR404A, THR404E
• C-D: ALA176C, ALA176D, ALA182C, ALA182D, ALA403C, ALA403D, ARG209C, ARG209D, ARG210C, ARG210D, ARG379C, ARG379D, ASN177C, ASN177D, ASP168C, ASP168D, ASP405C, ASP405D, CYS406C, CYS406D, GLN371C, GLN371D, GLN374C, GLN374D, GLU174C, GLU174D, GLU183C, GLU183D, GLU187C, GLU187D, GLU203C, GLU203D, GLU213C, GLU213D, GLU372C, GLU372D, GLU373C, GLU373D, GLY173C, GLY173D, GLY185C, GLY185D, GLY188D, GLY407C, GLY407D, ILE184C, ILE184D, ILE381C, ILE381D, LEU178C, LEU178D, LEU376C, LEU376D, LEU378C, LEU378D, LEU380C, LEU380D, LEU402C, LEU402D, LYS180C, LYS180D, LYS186C, LYS186D, LYS375C, LYS375D, LYS382C, LYS382D, LYS401C, LYS401D, MET181C, MET181D, MET206C, MET206D, MET377C, MET377D, MET398C, MET398D, PHE167C, PHE167D, PHE169C, PHE169D, PHE204C, PHE204D, PRO171C, PRO171D, PRO175C, PRO175D, PRO202C, PRO202D, SER207C, SER207D, THR170C, THR170D, THR179C, THR179D, THR205C, THR205D, THR404C, THR404D
• C-E: ARG220C, ARG220E, ASP217C, ASP217E, ILE218C, ILE218E, LYS221C, LYS221E
• D-E: ALA351D, ALA351E, ALA353D, ALA353E, ALA482D, ALA482E, ARG343D, ARG343E, ARG350D, ARG350E, ARG394D, ARG394E, ARG456D, ARG456E, ARG458D, ARG458E, ARG459D, ARG459E, ARG489D, ARG489E, ARG544D, ARG544E, ARG545D, ARG545E, ARG88D, ASN201D, ASN201E, ASN337D, ASN337E, ASN346D, ASN346E, ASN418D, ASN418E, ASP417D, ASP417E, ASP443D, ASP443E, ASP449D, ASP449E, ASP457D, ASP457E, ASP45D, ASP45E, ASP474D, ASP474E, ASP485D, ASP485E, ASP51D, ASP51E, GLN347D, GLN347E, GLN371D, GLN371E, GLN396D, GLN396E, GLU110D, GLU19D, GLU19E, GLU200D, GLU200E, GLU354D, GLU354E, GLU392D, GLU392E, GLU420D, GLU420E, GLU44D, GLU44E, GLU463D, GLU463E, GLU464D, GLU464E, GLU46D, GLU46E, GLU540D, GLU540E, GLU554D, GLU554E, GLY18D, GLY18E, GLY336D, GLY336E, GLY352D, GLY352E, GLY391D, GLY391E, GLY444D, GLY444E, GLY446D, GLY446E, GLY448D, GLY448E, GLY451D, GLY451E, GLY465D, GLY465E, GLY483D, GLY483E, GLY490D, GLY490E, GLY49D, GLY49E, HIS357D, HIS357E, ILE20D, ILE20E, ILE334D, ILE334E, ILE339D, ILE339E, ILE345D, ILE345E, ILE415D, ILE415E, ILE442D, ILE442E, ILE447D, ILE447E, ILE450D, ILE450E, ILE453D, ILE453E, ILE460D, ILE460E, ILE468D, ILE468E, ILE473D, ILE473E, ILE480D, ILE480E, ILE487D, ILE487E, ILE50D, ILE50E, ILE548D, ILE551D, ILE551E, ILE552D, ILE552E, LEU17D, LEU17E, LEU348D, LEU348E, LEU360D, LEU360E, LEU455D, LEU455E, LEU461D, LEU461E, LEU466D, LEU466E, LEU47D, LEU47E, LEU486D, LEU486E, LEU48D, LEU48E, LEU500D, LEU500E, LEU538D, LEU538E, LEU549D, LEU549E, LYS397D, LYS397E, LYS41D, LYS41E, LYS527D, LYS527E, LYS541D, LYS541E, LYS543D, LYS543E, MET395D, MET395E, MET398D, MET398E, MET416D, MET416E, MET547D, MET547E, MET553D, MET553E, PHE491D, PHE491E, PRO202D, PRO202E, PRO304D, PRO304E, PRO333D, PRO333E, PRO335D, PRO335E, PRO484D, PRO484E, PRO546D, PRO546E, PRO550D, PRO550E, SER340D, SER340E, SER342D, SER342E, SER445D, SER445E, SER462D, SER462E, SER472D, SER472E, SER481D, SER481E, SER488D, SER488E, THR338D, THR338E, THR344D, THR344E, THR542D, THR542E, TRP523D, TRP523E, TYR349D, TYR349E, TYR393D, TYR393E, TYR441E, TYR539D, TYR539E, VAL341D, VAL341E, VAL355D, VAL355E, VAL454D, VAL454E, VAL467D, VAL467E, VAL469D, VAL469E, VAL470D, VAL470E, VAL471D, VAL471E, VAL492D, VAL492E, VAL555D, VAL555E